Flight Attendant Medical Research Institute Publications and Presentations: 2017

Publications and Presentations: 2017

Abston E, Comellas A, Reed RM, Kim V, Wise RA, Brower R, Fortis S, Beichel R, Bhatt S, Zabner J, Newell J, Hoffman EA, Eberlein M. Higher BMI is associated with higher expiratory airflow normalised for lung volume (FEF25-75/FVC) in COPD. BMJ Open Respir Res. 2017;4(1):e000231.

Advani J, Subbannayya Y, Patel K, Khan AA, Patil AH, Jain AP, Solanki HS, Radhakrishnan A, Pinto SM, Sahasrabuddhe NA, Thomas JK, Mathur PP, Nair BG, Chang X, Prasad TSK, Sidransky D, Gowda H, Chatterjee A. Long-Term Cigarette Smoke Exposure and Changes in MiRNA Expression and Proteome in Non-Small-Cell Lung Cancer. OMICS. 2017;21(7):390-403.

Aksoy MO, Kim V, Cornwell WD, Rogers TJ, Kosmider B, Bahmed K, Barrero C, Merali S, Shetty N, Kelsen SG. Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers. Respir Res. 2017;18(1):78.

Alon R. A Sweet Solution: Glycolysis-Dependent Treg Cell Migration. Immunity. 2017;47(5):805-807.

Alon R, van Buul JD. Leukocyte Breaching of Endothelial Barriers: The Actin Link. Trends Immunol. 2017;38(8):606-615.

Aravamudan B, Goorhouse KJ, Unnikrishnan G, Thompson MA, Pabelick CM, Hawse JR, Prakash YS, Sathish V. Differential Expression of Estrogen Receptor Variants in Response to Inflammation Signals in Human Airway Smooth Muscle. J Cell Physiol. 2017;232(7):1754-1760.

Aravamudan B, Thompson M, Sieck GC, Vassallo R, Pabelick CM, Prakash YS. Functional Effects of Cigarette Smoke-Induced Changes in Airway Smooth Muscle Mitochondrial Morphology. J Cell Physiol. 2017;232(5):1053-1068.

Bagam P, Singh DP, Inda ME, Batra S. Unraveling the role of membrane microdomains during microbial infections. Cell Biol Toxicol. 2017.

Barzilai S, Yadav SK, Morrell S, Roncato F, Klein E, Stoler-Barak L, Golani O, Feigelson SW, Zemel A, Nourshargh S, Alon R. Leukocytes Breach Endothelial Barriers by Insertion of Nuclear Lobes and Disassembly of Endothelial Actin Filaments. Cell Rep. 2017;18(3):685-699.

Bednash JS, Weathington N, Londino J, Rojas M, Gulick DL, Fort R, Han S, McKelvey AC, Chen BB, Mallampalli RK. Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity. Nat Commun. 2017;8:15203.

Boija A, Mahat DB, Zare A, Holmqvist PH, Philip P, Meyers DJ, Cole PA, Lis JT, Stenberg P, Mannervik M. CBP Regulates Recruitment and Release of Promoter-Proximal RNA Polymerase II. Mol Cell. 2017;68(3):491-503 e495.

Brown KE, Sin DD, Voelker H, Connett JE, Niewoehner DE, Kunisaki KM, Network CCR. Serum bilirubin and the risk of chronic obstructive pulmonary disease exacerbations. Respir Res. 2017;18(1):179.

Broxterman RM, Layec G, Hureau TJ, Amann M, Richardson RS. Skeletal muscle bioenergetics during all-out exercise: mechanistic insight into the oxygen uptake slow component and neuromuscular fatigue. J Appl Physiol (1985). 2017;122(5):1208-1217.

Broxterman RM, Layec G, Hureau TJ, Morgan DE, Bledsoe AD, Jessop JE, Amann M, Richardson RS. Bioenergetics and ATP Synthesis during Exercise: Role of Group III/IV Muscle Afferents. Med Sci Sports Exerc. 2017;49(12):2404-2413.

Cai P, Kovacs L, Dong S, Wu G, Su Y. BMP4 inhibits PDGF-induced proliferation and collagen synthesis via PKA-mediated inhibition of calpain-2 in pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2017;312(5):L638-L648.

Carson JL, Zhou L, Brighton L, Mills KH, Zhou H, Jaspers I, Hazucha M. Temporal structure/function variation in cultured differentiated human nasal epithelium associated with acute single exposure to tobacco smoke or E-cigarette vapor. Inhal Toxicol. 2017;29(3):137-144.

Charni M, Aloni-Grinstein R, Molchadsky A, Rotter V. p53 on the crossroad between regeneration and cancer. Cell Death Differ. 2017;24(1):8-14.

Cheemarla NR, Banos-Lara MDR, Naidu S, Guerrero-Plata A. Neutrophils regulate the lung inflammatory response via gammadelta T cell infiltration in an experimental mouse model of human metapneumovirus infection. J Leukoc Biol. 2017;101(6):1383-1392.

Cheemarla NR, Guerrero-Plata A. Human Metapneumovirus Attachment Protein Contributes to Neutrophil Recruitment into the Airways of Infected Mice. Viruses. 2017;9(10).

Chen C, Mangoni ML, Di YP. In vivo therapeutic efficacy of frog skin-derived peptides against Pseudomonas aeruginosa-induced pulmonary infection. Sci Rep. 2017;7(1):8548.

Chen X, Li K, Yip R, Perumalswami P, Branch AD, Lewis S, Del Bello D, Becker BJ, Yankelevitz DF, Henschke CI. Hepatic steatosis in participants in a program of low-dose CT screening for lung cancer. Eur J Radiol. 2017;94:174-179.

Chen Y, Vasquez MM, Zhu L, Lizarraga RE, Krutzsch M, Einspahr J, Alberts DS, Di PYP, Martinez FD, Guerra S. Effects of Retinoids on Augmentation of Club Cell Secretory Protein. Am J Respir Crit Care Med. 2017;196(7):928-931.

Christoforou N, Chakraborty S, Kirkton RD, Adler AF, Addis RC, Leong KW. Core Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell Lineage. Sci Rep. 2017;7:40285.

Clark CM, Guerrero-Plata A. Respiratory Syncytial Virus Vaccine Approaches: a Current Overview. Curr Clin Microbiol Rep. 2017;4:202-207.

Collaco JM, Aherrera AD, McGrath-Morrow SA. The influence of gender on respiratory outcomes in children with bronchopulmonary dysplasia during the first 3 years of life. Pediatr Pulmonol. 2017;52(2):217-224.

Dai Q, Moshitch-Moshkovitz S, Han D, Kol N, Amariglio N, Rechavi G, Dominissini D, He C. Nm-seq maps 2′-O-methylation sites in human mRNA with base precision. Nat Methods. 2017;14(7):695-698.

Dandachi N, Kelly NJ, Wood JP, Burton CL, Radder JE, Leme AS, Gregory AD, Shapiro SD. Macrophage Elastase Induces TRAIL-mediated Tumor Cell Death through Its Carboxy-Terminal Domain. Am J Respir Crit Care Med. 2017;196(3):353-363.

Deslouches B, Di YP. Antimicrobial peptides with selective antitumor mechanisms: prospect for anticancer applications. Oncotarget. 2017;8(28):46635-46651.

Ding Q, Subramanian I, Luckhardt TR, Che P, Waghray M, Zhao XK, Bone N, Kurundkar AR, Hecker L, Hu M, Zhou Y, Horowitz JC, Vittal R, Thannickal VJ. Focal adhesion kinase signaling determines the fate of lung epithelial cells in response to TGF-beta. Am J Physiol Lung Cell Mol Physiol. 2017;312(6):L926-L935.

Drehmer JE, Hipple B, Ossip DJ, Nabi-Burza E, Winickoff JP. A Cross-Sectional Study of Happiness and Smoking Cessation among Parents. J Smok Cessat. 2017;12(1):6-14.

Drouin O, McMillen RC, Klein JD, Winickoff JP. E-Cigarette Advice to Patients From Physicians and Dentists in the United States. Am J Health Promot. 2017:890117117710876.

Duffy S, Marron R, Voelker H, Albert R, Connett J, Bailey W, Casaburi R, Cooper JA, Jr., Curtis JL, Dransfield M, Han MK, Make B, Marchetti N, Martinez F, Lazarus S, Niewoehner D, Scanlon PD, Sciurba F, Scharf S, Reed RM, Washko G, Woodruff P, McEvoy C, Aaron S, Sin D, Criner GJ, Network NCCR, the Canadian Institutes of Health R. Effect of beta-blockers on exacerbation rate and lung function in chronic obstructive pulmonary disease (COPD). Respir Res. 2017;18(1):124.

Eberlein M, Reed RM, Chahla M, Bolukbas S, Blevins A, Van Raemdonck D, Stanzi A, Inci I, Marasco S, Shigemura N, Aigner C, Deuse T. Lobar lung transplantation from deceased donors: A systematic review. World J Transplant. 2017;7(1):70-80.

Eberlein M, Reed RM, Redwan B, Bolukbas S. Persistent Air Leaks. Chest. 2017;152(2):449-450.

Florence JM, Krupa A, Booshehri LM, Allen TC, Kurdowska AK. Metalloproteinase-9 contributes to endothelial dysfunction in atherosclerosis via protease activated receptor-1. PLoS One. 2017;12(2):e0171427.

Flores RM, Nicastri D, Bauer T, Aye R, Andaz S, Kohman L, Sheppard B, Mayfield W, Thurer R, Korst R, Straznicka M, Grannis F, Pass H, Connery C, Yip R, Smith JP, Yankelevitz DF, Henschke CI, Altorki NK, Writing committee for the IEI. Computed Tomography Screening for Lung Cancer: Mediastinal Lymph Node Resection in Stage IA Nonsmall Cell Lung Cancer Manifesting as Subsolid and Solid Nodules. Ann Surg. 2017;265(5):1025-1033.

Fusaro MV, Nielsen ND, Nielsen A, Fontaine MJ, Hess JR, Reed RM, DeLisle S, Netzer G. Restrictive versus liberal red blood cell transfusion strategy after hip surgery: a decision model analysis of healthcare costs. Transfusion. 2017;57(2):357-366.

George P, Srivastava MC, Ludmir J, Reed RM, Tewelde SZ, Gupta A, McCurdy MT. Augmenting Function for Infarction from Infection: Impella 2.5 for Ischemic Cardiogenic Shock Complicating Sepsis. Case Rep Cardiol. 2017;2017:8407530.

Geraghty P, Hadas E, Kim BH, Dabo AJ, Volsky DJ, Foronjy R. HIV infection model of chronic obstructive pulmonary disease in mice. Am J Physiol Lung Cell Mol Physiol. 2017;312(4):L500-L509.

Ghosh M, Ahmad S, White CW, Reynolds SD. Transplantation of Airway Epithelial Stem/Progenitor Cells: A Future for Cell-Based Therapy. Am J Respir Cell Mol Biol. 2017;56(1):1-10.

Gomez JL, Kaminski N. Toward Precision Medicine of Symptom Control in Asthma. Am J Respir Crit Care Med. 2017;195(2):147-148.

Gomez JL, Yan X, Holm CT, Grant N, Liu Q, Cohn L, Nezgovorova V, Meyers DA, Bleecker ER, Crisafi GM, Jarjour NN, Rogers L, Reibman J, Chupp GL, Investigators S. Characterisation of asthma subgroups associated with circulating YKL-40 levels. Eur Respir J. 2017;50(4).

Goodrich AC, Meyers DJ, Frueh DP. Molecular impact of covalent modifications on nonribosomal peptide synthetase carrier protein communication. J Biol Chem. 2017;292(24):10002-10013.

Groner JA, Huang H, Joshi MS, Eastman N, Nicholson L, Bauer JA. Secondhand Smoke Exposure and Preclinical Markers of Cardiovascular Risk in Toddlers. J Pediatr. 2017;189:155-161.

Han S, Jerome JA, Gregory AD, Mallampalli RK. Cigarette smoke destabilizes NLRP3 protein by promoting its ubiquitination. Respir Res. 2017;18(1):2.

Head SA, Shi WQ, Yang EJ, Nacev BA, Hong SY, Pasunooti KK, Li RJ, Shim JS, Liu JO. Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis. ACS Chem Biol. 2017;12(1):174-182.

Hecht HS, Cronin P, Blaha MJ, Budoff MJ, Kazerooni EA, Narula J, Yankelevitz D, Abbara S. 2016 SCCT/STR guidelines for coronary artery calcium scoring of noncontrast noncardiac chest CT scans: A report of the Society of Cardiovascular Computed Tomography and Society of Thoracic Radiology. J Thorac Imaging. 2017;32(5):W54-W66.

Heerma van Voss MR, Brilliant JD, Vesuna F, Bol GM, van der Wall E, van Diest PJ, Raman V. Combination treatment using DDX3 and PARP inhibitors induces synthetic lethality in BRCA1-proficient breast cancer. Med Oncol. 2017;34(3):33.

Heerma van Voss MR, Schrijver WA, Ter Hoeve ND, Hoefnagel LD, Manson QF, van der Wall E, Raman V, van Diest PJ, Dutch Distant Breast Cancer Metastases C. The prognostic effect of DDX3 upregulation in distant breast cancer metastases. Clin Exp Metastasis. 2017;34(1):85-92.

Heerma van Voss MR, Vesuna F, Bol GM, Meeldijk J, Raman A, Offerhaus GJ, Buerger H, Patel AH, van der Wall E, van Diest PJ, Raman V. Nuclear DDX3 expression predicts poor outcome in colorectal and breast cancer. Onco Targets Ther. 2017;10:3501-3513.

Heidecker B, Spencer RM, Hayes V, Hall S, Parikh N, Stock EO, Redberg R. High Prevalence and Clinical/Sociodemographic Correlates of Miscarriages Among Flight Attendants. Am J Med. 2017.

Hernandez-Saavedra D, Sanders L, Perez MJ, Kosmider B, Smith LP, Mitchell JD, Yoshida T, Tuder RM. RTP801 Amplifies Nicotinamide Adenine Dinucleotide Phosphate Oxidase-4-Dependent Oxidative Stress Induced by Cigarette Smoke. Am J Respir Cell Mol Biol. 2017;56(1):62-73.

Hoti N, Yang S, Aiyetan P, Kumar B, Hu Y, Clark D, Eroglu AU, Shah P, Johnson T, Chowdery WH, Zhang H, Rodriguez R. Overexpression of Exportin-5 Overrides the Inhibitory Effect of miRNAs Regulation Control and Stabilize Proteins via Posttranslation Modifications in Prostate Cancer. Neoplasia. 2017;19(10):817-829.

Hough KP, Chanda D, Duncan SR, Thannickal VJ, Deshane JS. Exosomes in immunoregulation of chronic lung diseases. Allergy. 2017;72(4):534-544.

Jacob P, 3rd, Benowitz NL, Destaillats H, Gundel L, Hang B, Martins-Green M, Matt GE, Quintana PJ, Samet JM, Schick SF, Talbot P, Aquilina NJ, Hovell MF, Mao JH, Whitehead TP. Thirdhand Smoke: New Evidence, Challenges, and Future Directions. Chem Res Toxicol. 2017;30(1):270-294.

Jang JH, Chand HS, Bruse S, Doyle-Eisele M, Royer C, McDonald J, Qualls C, Klingelhutz AJ, Lin Y, Mallampalli R, Tesfaigzi Y, Nyunoya T. Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD Severity. COPD. 2017;14(2):228-237.

Jin L, Batra S, Jeyaseelan S. Deletion of Nlrp3 Augments Survival during Polymicrobial Sepsis by Decreasing Autophagy and Enhancing Phagocytosis. J Immunol. 2017;198(3):1253-1262.

Jin L, Batra S, Jeyaseelan S. Diminished neutrophil extracellular trap (NET) formation is a novel innate immune deficiency induced by acute ethanol exposure in polymicrobial sepsis, which can be rescued by CXCL1. PLoS Pathog. 2017;13(9):e1006637.

Jubinville E, Talbot M, Berube JC, Hamel-Auger M, Maranda-Robitaille M, Beaulieu MJ, Aubin S, Pare ME, Kallend DG, Arsenault B, Bosse Y, Morissette MC. Interplay between cigarette smoking and pulmonary reverse lipid transport. Eur Respir J. 2017;50(3).

Kalchiem-Dekel O, Reed RM. Statins in COPD: Life After STATCOPE. Chest. 2017;152(3):456-457.

Kaza N, Raju SV, Cadillac JM, Trombley JA, Rasmussen L, Tang L, Dohm E, Harrod KS, Rowe SM. Use of ferrets for electrophysiologic monitoring of ion transport. PLoS One. 2017;12(10):e0186984.

Kelly NJ, Radder JE, Baust JJ, Burton CL, Lai YC, Potoka KC, Agostini BA, Wood JP, Bachman TN, Vanderpool RR, Dandachi N, Leme AS, Gregory AD, Morris A, Mora AL, Gladwin MT, Shapiro SD. Mouse Genome-Wide Association Study of Preclinical Group II Pulmonary Hypertension Identifies Epidermal Growth Factor Receptor. Am J Respir Cell Mol Biol. 2017;56(4):488-496.

Kim BS, Tilstam PV, Hwang SS, Simons D, Schulte W, Leng L, Sauler M, Ganse B, Averdunk L, Kopp R, Stoppe C, Bernhagen J, Pallua N, Bucala R. D-dopachrome tautomerase in adipose tissue inflammation and wound repair. J Cell Mol Med. 2017;21(1):35-45.

Kim LY, McGrath-Morrow SA, McMillen R, Collaco JM. Smoking Patterns and Perspectives of Families of Infants with Bronchopulmonary Dysplasia. Pediat Aller Imm Pul. 2017;30(1):26-30.

Kohanski MA, Tharakan A, London NR, Lane AP, Ramanathan M, Jr. Bactericidal antibiotics promote oxidative damage and programmed cell death in sinonasal epithelial cells. Int Forum Allergy Rhinol. 2017;7(4):359-364.

Kosowicz JG, Lee J, Peiffer B, Guo Z, Chen J, Liao G, Hayward SD, Liu JO, Ambinder RF. Drug Modulators of B Cell Signaling Pathways and Epstein-Barr Virus Lytic Activation. J Virol. 2017;91(16).

Kovacs L, Su Y. Redox-Dependent Calpain Signaling in Airway and Pulmonary Vascular Remodeling in COPD. Adv Exp Med Biol. 2017;967:139-160.

Krick S, Baumlin N, Aller SP, Aguiar C, Grabner A, Sailland J, Mendes E, Schmid A, Qi L, David NV, Geraghty P, King G, Birket SE, Rowe SM, Faul C, Salathe M. Klotho Inhibits Interleukin-8 Secretion from Cystic Fibrosis Airway Epithelia. Sci Rep. 2017;7(1):14388.

Krutsinger D, Pezzulo A, Blevins AE, Reed RM, Voigt MD, Eberlein M. Idiopathic hyperammonemia after solid organ transplantation: Primarily a lung problem? A single-center experience and systematic review. Clin Transplant. 2017;31(5).

Kumar V, Fleming T, Terjung S, Gorzelanny C, Gebhardt C, Agrawal R, Mall MA, Ranzinger J, Zeier M, Madhusudhan T, Ranjan S, Isermann B, Liesz A, Deshpande D, Haring HU, Biswas SK, Reynolds PR, Hammes HP, Peperkok R, Angel P, Herzig S, Nawroth PP. Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair. Nucleic Acids Res. 2017;45(18):10595-10613.

Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi K, Langston JW, Weinert BT, Choudhary C, de Vries P, Van Drie JH, McElligott D, Kesicki E, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A, Bromberg KD. Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature. 2017;550(7674):128-132.

Laube BL, Afshar-Mohajer N, Koehler K, Chen G, Lazarus P, Collaco JM, McGrath-Morrow SA. Acute and chronic in vivo effects of exposure to nicotine and propylene glycol from an E-cigarette on mucociliary clearance in a murine model. Inhal Toxicol. 2017;29(5):197-205.

Layec G, Hart CR, Trinity JD, Kwon OS, Rossman MJ, Broxterman RM, Le Fur Y, Jeong EK, Richardson RS. Oxygen delivery and the restoration of the muscle energetic balance following exercise: implications for delayed muscle recovery in patients with COPD. Am J Physiol Endocrinol Metab. 2017;313(1):E94-E104.

Leitao Filho FS, Won Ra S, Mattman A, Schellenberg RS, Fishbane N, Criner GJ, Woodruff PG, Lazarus SC, Albert R, Connett JE, Han MK, Martinez FJ, Leung JM, Man SFP, Aaron SD, Reed RM, Sin DD. Serum IgG and risk of exacerbations and hospitalizations in chronic obstructive pulmonary disease. J Allergy Clin Immunol. 2017;140(4):1164-1167 e1166.

Lendermon EA, Coon TA, Bednash JS, Weathington NM, McDyer JF, Mallampalli RK. Azithromycin decreases NALP3 mRNA stability in monocytes to limit inflammasome-dependent inflammation. Respir Res. 2017;18(1):131.

Lewis BW, Sultana R, Sharma R, Noel A, Langohr I, Patial S, Penn AL, Saini Y. Early Postnatal Secondhand Smoke Exposure Disrupts Bacterial Clearance and Abolishes Immune Responses in Muco-Obstructive Lung Disease. J Immunol. 2017;199(3):1170-1183.

Lewis JB, Hirschi KM, Arroyo JA, Bikman BT, Kooyman DL, Reynolds PR. Plausible Roles for RAGE in Conditions Exacerbated by Direct and Indirect (Secondhand) Smoke Exposure. Int J Mol Sci. 2017;18(3).

Lewis JB, Mejia C, Jordan C, Monson TD, Bodine JS, Dunaway TM, Egbert KM, Lewis AL, Wright TJ, Ogden KC, Broberg DS, Hall PD, Nelson SM, Hirschi KM, Reynolds PR, Arroyo JA. Inhibition of the receptor for advanced glycation end-products (RAGE) protects from secondhand smoke (SHS)-induced intrauterine growth restriction IUGR in mice. Cell Tissue Res. 2017;370(3):513-521.

Li K, Yip R, Avila R, Henschke CI, Yankelevitz DF. Size and Growth Assessment of Pulmonary Nodules: Consequences of the Rounding. J Thorac Oncol. 2017;12(4):657-662.

Liang M, Yip R, Tang W, Xu D, Reeves A, Henschke CI, Yankelevitz DF. Variation in Screening CT-Detected Nodule Volumetry as a Function of Size. AJR Am J Roentgenol. 2017;209(2):304-308.

Lilley M, Farassati F. The role of KPNbeta1 in neuro-oncology. Onco Targets Ther. 2017;10:2067-2068.

Lindow JC, Wunder EA, Jr., Popper SJ, Min JN, Mannam P, Srivastava A, Yao Y, Hacker KP, Raddassi K, Lee PJ, Montgomery RR, Shaw AC, Hagan JE, Araujo GC, Nery N, Jr., Relman DA, Kim CC, Reis MG, Ko AI. Correction: Cathelicidin Insufficiency in Patients with Fatal Leptospirosis. PLoS Pathog. 2017;13(9):e1006646.

Liu S, Xie Y, Jirapatnakul A, Reeves AP. Pulmonary nodule classification in lung cancer screening with three-dimensional convolutional neural networks. J Med Imaging (Bellingham). 2017;4(4):041308.

Liu X, Ma S, Turino G, Cantor J. The Pattern of Elastic Fiber Breakdown in Bleomycin-Induced Pulmonary Fibrosis May Reflect Microarchitectural Changes. Lung. 2017;195(1):93-99.

London NR, Jr., Tharakan A, Lane AP, Biswal S, Ramanathan M, Jr. Nuclear erythroid 2-related factor 2 activation inhibits house dust mite-induced sinonasal epithelial cell barrier dysfunction. Int Forum Allergy Rhinol. 2017;7(5):536-541.


Lu YY, Zhao XK, Yu L, Qi F, Zhai B, Gao CQ, Ding Q. Interaction of Src and Alpha-V Integrin Regulates Fibroblast Migration and Modulates Lung Fibrosis in A Preclinical Model of Lung Fibrosis. Sci Rep. 2017;7:46357.

Lyu J, Yang EJ, Head SA, Ai N, Zhang B, Wu C, Li RJ, Liu Y, Yang C, Dang Y, Kwon HJ, Ge W, Liu JO, Shim JS. Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth. Cancer Lett. 2017;409:91-103.

Marshall JD, Sauler M, Tonelli A, Rao Y, Bucala R, Lee PJ, Fares WH. Complexity of macrophage migration inhibitory factor (MIF) and other angiogenic biomarkers profiling in pulmonary arterial hypertension. Pulm Circ. 2017;7(3):730-733.

Matta B, Song S, Li D, Barnes BJ. Interferon regulatory factor signaling in autoimmune disease. Cytokine. 2017;98:15-26.

Mazza D, McGrath-Morrow S, Collaco JM. Use and perceptions of electronic cigarettes among caregivers of infants and children with bronchopulmonary dysplasia. Pediatric Allergy, Immunology, and Pulmonology 2017;30(3).

McClary B, Zinshteyn B, Meyer M, Jouanneau M, Pellegrino S, Yusupova G, Schuller A, Reyes JCP, Lu J, Guo Z, Ayinde S, Luo C, Dang Y, Romo D, Yusupov M, Green R, Liu JO. Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A. Cell Chem Biol. 2017;24(5):605-613 e605.

McMillen R, O’Connor KG, Groner J, Tanski S, Park ER, Klein JD. Changes and Factors Associated With Tobacco Counseling: Results From the AAP Periodic Survey. Acad Pediatr. 2017;17(5):504-514.

Mejia C, Lewis J, Jordan C, Mejia J, Ogden C, Monson T, Winden D, Watson M, Reynolds PR, Arroyo JA. Decreased activation of placental mTOR family members is associated with the induction of intrauterine growth restriction by secondhand smoke in the mouse. Cell Tissue Res. 2017;367(2):387-395.

Minkin R, Sandhu G, Grosu H, Tartell L, Ma S, Lin YY, Eden E, Turino GM. Desmosine and Isodesmosine as a Novel Biomarker for Pulmonary Arterial Hypertension: A Pilot Study. Am J Ther. 2017;24(4):e399-e404.

Moghadam AR, Patrad E, Tafsiri E, Peng W, Fangman B, Pluard TJ, Accurso A, Salacz M, Shah K, Ricke B, Bi D, Kimura K, Graves L, Najad MK, Dolatkhah R, Sanaat Z, Yazdi M, Tavakolinia N, Mazani M, Amani M, Ghavami S, Gartell R, Reilly C, Naima Z, Esfandyari T, Farassati F. Ral signaling pathway in health and cancer. Cancer Med. 2017;6(12):2998-3013.

Molchadsky A, Rotter V. p53 and its mutants on the slippery road from stemness to carcinogenesis. Carcinogenesis. 2017;38(4):347-358.

Mukherjee S, Subramaniam R, Chen H, Smith A, Keshava S, Shams H. Boosting efferocytosis in alveolar space using BCG vaccine to protect host against influenza pneumonia. PLoS One. 2017;12(7):e0180143.

Mulligan JK, O’Connell BP, Pasquini W, Mulligan RM, Smith S, Soler ZM, Atkinson C, Schlosser RJ. Impact of tobacco smoke on upper airway dendritic cell accumulation and regulation by sinonasal epithelial cells. Int Forum Allergy Rhinol. 2017;7(8):777-785.

Mulligan JK, Pasquini WN, Carroll WW, Williamson T, Reaves N, Patel KJ, Mappus E, Schlosser RJ, Atkinson C. Dietary vitamin D3 deficiency exacerbates sinonasal inflammation and alters local 25(OH)D3 metabolism. PLoS One. 2017;12(10):e0186374.

Muthumalage T, Pritsos K, Hunter K, Pritsos C. Commonly used air filters fail to eliminate secondhand smoke induced oxidative stress and inflammatory responses. Toxicol Mech Methods. 2017;27(6):458-466.

Nagano T, Lubling Y, Varnai C, Dudley C, Leung W, Baran Y, Mendelson Cohen N, Wingett S, Fraser P, Tanay A. Cell-cycle dynamics of chromosomal organization at single-cell resolution. Nature. 2017;547(7661):61-67.

Ngo K, Pohl P, Wang D, Leme AS, Lee J, Di P, Roughley P, Robbins PD, Niedernhofer LJ, Sowa G, Kang JD, Shapiro SS, Vo NV. ADAMTS5 Deficiency Protects Mice From Chronic Tobacco Smoking-induced Intervertebral Disc Degeneration. Spine (Phila Pa 1976). 2017;42(20):1521-1528.

Nickel S, Selo MA, Fallack J, Clerkin CG, Huwer H, Schneider-Daum N, Lehr CM, Ehrhardt C. Expression and Activity of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Distal Lung Epithelial Cells In Vitro. Pharm Res. 2017;34(12):2477-2487.

Nishida K, Brune KA, Putcha N, Mandke P, O’Neal WK, Shade D, Srivastava V, Wang M, Lam H, An SS, Drummond MB, Hansel NN, Robinson DN, Sidhaye VK. Cigarette smoke disrupts monolayer integrity by altering epithelial cell-cell adhesion and cortical tension. Am J Physiol Lung Cell Mol Physiol. 2017;313(3):L581-L591.

Ooki A, Maleki Z, Tsay JJ, Goparaju C, Brait M, Turaga N, Nam HS, Rom WN, Pass HI, Sidransky D, Guerrero-Preston R, Hoque MO. A Panel of Novel Detection and Prognostic Methylated DNA Markers in Primary Non-Small Cell Lung Cancer and Serum DNA. Clin Cancer Res. 2017;23(22):7141-7152.

Osgood RS, Upham BL, Bushel PR, Velmurugan K, Xiong KN, Bauer AK. Secondhand Smoke-Prevalent Polycyclic Aromatic Hydrocarbon Binary Mixture-Induced Specific Mitogenic and Pro-inflammatory Cell Signaling Events in Lung Epithelial Cells. Toxicol Sci. 2017;157(1):156-171.

Payne P, Fiering S, Leiter JC, Zava DT, Crane-Godreau MA. Effectiveness of a Novel Qigong Meditative Movement Practice for Impaired Health in Flight Attendants Exposed to Second-Hand Cigarette Smoke. Front Hum Neurosci. 2017;11:67.

Polverino F, Celli BR, Owen CA. Chronic Obstructive Pulmonary Disease: Breathing New Life into Old Cardiovascular Drugs? Ann Am Thorac Soc. 2017;14(11):1718.

Polverino F, Laucho-Contreras ME, Petersen H, Bijol V, Sholl LM, Choi ME, Divo M, Pinto-Plata V, Chetta A, Tesfaigzi Y, Celli BR, Owen CA. A Pilot Study Linking Endothelial Injury in Lungs and Kidneys in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017;195(11):1464-1476.

Prokocimer M, Molchadsky A, Rotter V. Dysfunctional diversity of p53 proteins in adult acute myeloid leukemia: projections on diagnostic workup and therapy. Blood. 2017;130(6):699-712.

Pourakbar S, Pluard TJ, Accurso AD, Farassati F. Ezh2, a novel target in detection and therapy of breast cancer [editorial]. Onco Targets Ther. 2017;10:2685-2687.

Puthusseri B, Marudamuthu A, Tiwari N, Fu J, Idell S, Shetty S. Regulation of p53-mediated changes in the uPA-fibrinolytic system and in lung injury by loss of surfactant protein C expression in alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2017;312(6):L783-L796.

Ra SW, Sze MA, Lee EC, Tam S, Oh Y, Fishbane N, Criner GJ, Woodruff PG, Lazarus SC, Albert R, Connett JE, Han MK, Martinez FJ, Aaron SD, Reed RM, Man SFP, Sin DD, Canadian Respiratory Research N. Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori. Respir Res. 2017;18(1):109.

Radder JE, Gregory AD, Leme AS, Cho MH, Chu Y, Kelly NJ, Bakke P, Gulsvik A, Litonjua AA, Sparrow D, Beaty TH, Crapo JD, Silverman EK, Zhang Y, Berndt A, Shapiro SD. Variable Susceptibility to Cigarette Smoke-Induced Emphysema in 34 Inbred Strains of Mice Implicates Abi3bp in Emphysema Susceptibility. Am J Respir Cell Mol Biol. 2017;57(3):367-375.

Radder JE, Zhang Y, Gregory AD, Yu S, Kelly NJ, Leader JK, Kaminski N, Sciurba FC, Shapiro SD. Extreme Trait Whole-Genome Sequencing Identifies PTPRO as a Novel Candidate Gene in Emphysema with Severe Airflow Obstruction. Am J Respir Crit Care Med. 2017;196(2):159-171.

Radhakrishnan A, Nanjappa V, Raja R, Sathe G, Puttamallesh VN, Jain AP, Pinto SM, Balaji SA, Chavan S, Sahasrabuddhe NA, Mathur PP, Kumar MM, Prasad TSK, Santosh V, Sukumar G, Califano JA, Rangarajan A, Sidransky D, Pandey A, Gowda H, Chatterjee A. Corrigendum: A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma. Sci Rep. 2017;7:46864.

Raju SV, Lin VY, Liu L, McNicholas CM, Karki S, Sloane PA, Tang L, Jackson PL, Wang W, Wilson L, Macon KJ, Mazur M, Kappes JC, DeLucas LJ, Barnes S, Kirk K, Tearney GJ, Rowe SM. The Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor Augments Mucociliary Clearance Abrogating Cystic Fibrosis Transmembrane Conductance Regulator Inhibition by Cigarette Smoke. Am J Respir Cell Mol Biol. 2017;56(1):99-108.

Raju SV, Rasmussen L, Sloane PA, Tang LP, Libby EF, Rowe SM. Roflumilast reverses CFTR-mediated ion transport dysfunction in cigarette smoke-exposed mice. Respir Res. 2017;18(1):173.

Ramanathan M, Jr., London NR, Jr., Tharakan A, Surya N, Sussan TE, Rao X, Lin SY, Toskala E, Rajagopalan S, Biswal S. Airborne Particulate Matter Induces Nonallergic Eosinophilic Sinonasal Inflammation in Mice. Am J Respir Cell Mol Biol. 2017;57(1):59-65.

Rao D, Perraud AL, Schmitz C, Gally F. Cigarette smoke inhibits LPS-induced FABP5 expression by preventing c-Jun binding to the FABP5 promoter. PLoS One. 2017;12(5):e0178021.

Rao SS, Mu Q, Zeng Y, Cai PC, Liu F, Yang J, Xia Y, Zhang Q, Song LJ, Zhou LL, Li FZ, Lin YX, Fang J, Greer PA, Shi HZ, Ma WL, Su Y, Ye H. Calpain-activated mTORC2/Akt pathway mediates airway smooth muscle remodelling in asthma. Clin Exp Allergy. 2017;47(2):176-189.

Reed RM, Borgan SM, Eberlein M, Goldklang M, Lewis J, Miller M, Navab M, Kim BS. Tobacco Smoke Exposure Reduces Paraoxonase Activity in a Murine Model. Int J Biomed Sci. 2017;13(1):20-25.

Reed RM, Dransfield MT, Eberlein M, Miller M, Netzer G, Pavlovich M, Pollin TI, Scharf SM, Shuldiner AR, Sin D, Mitchell BD. Gender differences in first and secondhand smoke exposure, spirometric lung function and cardiometabolic health in the old order Amish: A novel population without female smoking. PLoS One. 2017;12(3):e0174354.

Reeves AP, Xie Y, Liu S. Large-scale image region documentation for fully automated image biomarker algorithm development and evaluation. J Med Imaging (Bellingham). 2017;4(2):024505.

Rinne ST, Castaneda J, Lindenauer PK, Cleary PD, Paz HL, Gomez JL. Chronic Obstructive Pulmonary Disease Readmissions and Other Measures of Hospital Quality. Am J Respir Crit Care Med. 2017;196(1):47-55.

Rolle CE, Tan YC, Seiwert TY, Vora S, Kanteti R, Hasina R, Carey GB, Surati M, Weichselbaum RR, Lingen MW, Vokes EE, Salgia R. Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma. Oncotarget. 2017;8(12):18726-18734.

Sailland J, Grosche A, Baumlin N, Dennis JS, Schmid A, Krick S, Salathe M. Role of Smad3 and p38 Signalling in Cigarette Smoke-induced CFTR and BK dysfunction in Primary Human Bronchial Airway Epithelial Cells. Sci Rep. 2017;7(1):10506.

Sanders NT, Dutson DJ, Durrant JW, Lewis JB, Wilcox SH, Winden DR, Arroyo JA, Bikman BT, Reynolds PR. Cigarette smoke extract (CSE) induces RAGE-mediated inflammation in the Ca9-22 gingival carcinoma epithelial cell line. Arch Oral Biol. 2017;80:95-100.

Schmid A, Sailland J, Novak L, Baumlin N, Fregien N, Salathe M. Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways. FEBS Lett. 2017;591(21):3493-3506.

Segal LN, Clemente JC, Li Y, Ruan C, Cao J, Danckers M, Morris A, Tapyrik S, Wu BG, Diaz P, Calligaro G, Dawson R, van Zyl-Smit RN, Dheda K, Rom WN, Weiden MD. Anaerobic Bacterial Fermentation Products Increase Tuberculosis Risk in Antiretroviral-Drug-Treated HIV Patients. Cell Host Microbe. 2017;21(4):530-537 e534.

Sharma NS, Wille KM, Athira S, Zhi D, Hough KP, Diaz-Guzman E, Zhang K, Kumar R, Rangarajan S, Eipers P, Wang Y, Srivastava RK, Rodriguez Dager JV, Athar M, Morrow C, Hoopes CW, Chaplin DD, Thannickal VJ, Deshane JS. Distal airway microbiome is associated with immunoregulatory myeloid cell responses in lung transplant recipients. J Heart Lung Transplant. 2017.

Sheinboim D, Maza I, Dror I, Parikh S, Krupalnik V, Bell RE, Zviran A, Suita Y, Hakim O, Mandel-Gutfreund Y, Khaled M, Hanna JH, Levy C. OCT4 impedes cell fate redirection by the melanocyte lineage master regulator MITF in mouse ESCs. Nat Commun. 2017;8(1):1022.

Shetty SK, Tiwari N, Marudamuthu AS, Puthusseri B, Bhandary YP, Fu J, Levin J, Idell S, Shetty S. p53 and miR-34a Feedback Promotes Lung Epithelial Injury and Pulmonary Fibrosis. Am J Pathol. 2017;187(5):1016-1034.

Shetzer Y, Napchan Y, Kaufman T, Molchadsky A, Tal P, Goldfinger N, Rotter V. Immune deficiency augments the prevalence of p53 loss of heterozygosity in spontaneous tumors but not bi-directional loss of heterozygosity in bone marrow progenitors. Int J Cancer. 2017;140(6):1364-1369.

Shonkoff JP. Rethinking the Definition of Evidence-Based Interventions to Promote Early Childhood Development. Pediatrics. 2017;140(6).

Shonkoff JP, Radner JM, Foote N. Expanding the evidence base to drive more productive early childhood investment. Lancet. 2017;389(10064):14-16.

Singh DP, Bagam P, Sahoo MK, Batra S. Immune-related gene polymorphisms in pulmonary diseases. Toxicology. 2017;383:24-39.

Singh SP, Chand HS, Langley RJ, Mishra N, Barrett T, Rudolph K, Tellez C, Filipczak PT, Belinsky S, Saeed AI, Sheybani A, Exil V, Agarwal H, Sidhaye VK, Sussan T, Biswal S, Sopori M. Gestational Exposure to Sidestream (Secondhand) Cigarette Smoke Promotes Transgenerational Epigenetic Transmission of Exacerbated Allergic Asthma and Bronchopulmonary Dysplasia. J Immunol. 2017;198(10):3815-3822.

Sokoya M, Ramakrishnan VR, Frank DN, Rahkola J, Getz A, Kingdom TT, Kofonow JM, Nguyen Q, Janoff EN. Expression of immunoglobulin D is increased in chronic rhinosinusitis. Ann Allergy Asthma Immunol. 2017;119(4):317-323 e311.

Solanki HS, Advani J, Khan AA, Radhakrishnan A, Sahasrabuddhe NA, Pinto SM, Chang X, Prasad TSK, Mathur PP, Sidransky D, Gowda H, Chatterjee A. Chronic Cigarette Smoke Mediated Global Changes in Lung Mucoepidermoid Cells: A Phosphoproteomic Analysis. OMICS. 2017;21(8):474-487.

Solomon H, Brauning B, Fainer I, Ben-Nissan G, Rabani S, Goldfinger N, Moscovitz O, Shakked Z, Rotter V, Sharon M. Post-translational regulation of p53 function through 20S proteasome-mediated cleavage. Cell Death Differ. 2017;24(12):2187-2198.

Solomon O, Di Segni A, Cesarkas K, Porath HT, Marcu-Malina V, Mizrahi O, Stern-Ginossar N, Kol N, Farage-Barhom S, Glick-Saar E, Lerenthal Y, Levanon EY, Amariglio N, Unger R, Goldstein I, Eyal E, Rechavi G. RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure. Nat Commun. 2017;8(1):1440.

Suber T, Wei J, Jacko AM, Nikolli I, Zhao Y, Zhao J, Mallampalli RK. SCFFBXO17 E3 ligase modulates inflammation by regulating proteasomal degradation of glycogen synthase kinase-3beta in lung epithelia. J Biol Chem. 2017;292(18):7452-7461.

Tanay A, Regev A. Scaling single-cell genomics from phenomenology to mechanism. Nature. 2017;541(7637):331-338.

Teng Y, Luo HR, Kambara H. Heterogeneity of neutrophil spontaneous death. Am J Hematol. 2017;92(8):E156-E159.

Torok MR, Winickoff JP, McMillen RC, Klein JD, Wilson KM. Prevalence and location of tobacco smoke exposure outside the home in adults and children in the United States. Public Health. 2017;151:149-159.

Tzouvelekis A, Yu G, Lino Cardenas CL, Herazo-Maya JD, Wang R, Woolard T, Zhang Y, Sakamoto K, Lee H, Yi JS, DeIuliis G, Xylourgidis N, Ahangari F, Lee PJ, Aidinis V, Herzog EL, Homer R, Bennett AM, Kaminski N. SH2 Domain-Containing Phosphatase-2 Is a Novel Antifibrotic Regulator in Pulmonary Fibrosis. Am J Respir Crit Care Med. 2017;195(4):500-514.

Uang R, Crosbie E, Glantz SA. Smokefree implementation in Colombia: Monitoring, outside funding, and business support. Salud Publica Mex. 2017;59(2):128-136.

van der Eijk Y, Glantz SA. Tobacco industry attempts to frame smoking as a ‘disability’ under the 1990 Americans with Disabilities Act. PLoS One. 2017;12(11):e0188188.

Vandivier RW, Ghosh M. Understanding the Relevance of the Mouse Cigarette Smoke Model of COPD: Peering through the Smoke. Am J Respir Cell Mol Biol. 2017;57(1):3-4.

Vaz Fragoso CA, Cain HC, Casaburi R, Lee PJ, Iannone L, Leo-Summers LS, Van Ness PH. Spirometry, Static Lung Volumes, and Diffusing Capacity. Respir Care. 2017;62(9):1137-1147.

Venturelli M, Layec G, Trinity J, Hart CR, Broxterman RM, Richardson RS. Single passive leg movement-induced hyperemia: a simple vascular function assessment without a chronotropic response. J Appl Physiol (1985). 2017;122(1):28-37.

Vij N. Nano-based rescue of dysfunctional autophagy in chronic obstructive lung diseases. Expert Opin Drug Deliv. 2017;14(4):483-489.

Vogel ER, Britt RD, Jr., Faksh A, Kuipers I, Pandya H, Prakash YS, Martin RJ, Pabelick CM. Moderate hyperoxia induces extracellular matrix remodeling by human fetal airway smooth muscle cells. Pediatr Res. 2017;81(2):376-383.

Wang T, Shimizu Y, Wu X, Kelly GT, Xu X, Wang L, Qian Z, Chen Y, Garcia JGN. Particulate matter disrupts human lung endothelial cell barrier integrity via Rho-dependent pathways. Pulm Circ. 2017;7(3):617-623.

White MM, Geraghty P, Hayes E, Cox S, Leitch W, Alfawaz B, Lavelle GM, McElvaney OJ, Flannery R, Keenan J, Meleady P, Henry M, Clynes M, Gunaratnam C, McElvaney NG, Reeves EP. Neutrophil Membrane Cholesterol Content is a Key Factor in Cystic Fibrosis Lung Disease. EBioMedicine. 2017;23:173-184.

Wilson KM, Torok MR, McMillen RC, Klein JD, Levy DE, Winickoff JP. Tobacco-Smoke Incursions and Satisfaction Among Residents With Children in Multiunit Housing, United States, 2013. Public Health Rep. 2017;132(6):637-645.

Wilson KM, Torok MR, Wei B, Wang L, Robinson M, Sosnoff CS, Blount BC. Detecting biomarkers of secondhand marijuana smoke in young children. Pediatr Res. 2017;81(4):589-592.

Wise RA, Holbrook JT, Criner G, Sethi S, Rayapudi S, Sudini KR, Sugar EA, Burke A, Thimmulappa R, Singh A, Talalay P, Fahey JW, Berenson CS, Jacobs MR, Biswal S, Broccoli Sprout Extract Trial Research G. Correction: Lack of Effect of Oral Sulforaphane Administration on Nrf2 Expression in COPD: A Randomized, Double-Blind, Placebo Controlled Trial. PLoS One. 2017;12(3):e0175077.

Wolf AS, Swanson SJ, Yip R, Liu B, Tarras ES, Yankelevitz DF, Henschke CI, Taioli E, Flores RM, Investigators IE. The Impact of Margins on Outcomes After Wedge Resection for Stage I Non-Small Cell Lung Cancer. Ann Thorac Surg. 2017;104(4):1171-1178.

Wu BG, Segal LN. Lung Microbiota and Its Impact on the Mucosal Immune Phenotype. Microbiol Spectr. 2017;5(3).

Yankelevitz DF, Cham MD, Hecht H, Yip R, Shemesh J, Narula J, Henschke CI. The Association of Secondhand Tobacco Smoke and CT Angiography-Verified Coronary Atherosclerosis. JACC Cardiovasc Imaging. 2017;10(6):652-659.

Yip R, Henschke CI, Xu DM, Li K, Jirapatnakul A, Yankelevitz DF. Lung Cancers Manifesting as Part-Solid Nodules in the National Lung Screening Trial. AJR Am J Roentgenol. 2017;208(5):1011-1021.

Zemski Berry KA, Murphy RC, Kosmider B, Mason RJ. Lipidomic characterization and localization of phospholipids in the human lung. J Lipid Res. 2017;58(5):926-933.

Zhang X, Liu P, Zhang C, Chiewchengchol D, Zhao F, Yu H, Li J, Kambara H, Luo KY, Venkataraman A, Zhou Z, Zhou W, Zhu H, Zhao L, Sakai J, Chen Y, Ho YS, Bajrami B, Xu B, Silberstein LE, Cheng T, Xu Y, Ke Y, Luo HR. Positive Regulation of Interleukin-1beta Bioactivity by Physiological ROS-Mediated Cysteine S-Glutathionylation. Cell Rep. 2017;20(1):224-235.

Zhao XK, Yu L, Cheng ML, Che P, Lu YY, Zhang Q, Mu M, Li H, Zhu LL, Zhu JJ, Hu M, Li P, Liang YD, Luo XH, Cheng YJ, Xu ZX, Ding Q. Focal Adhesion Kinase Regulates Hepatic Stellate Cell Activation and Liver Fibrosis. Sci Rep. 2017;7(1):4032.

Zhou X, Zhu L, Lizarraga R, Chen Y. Human Airway Epithelial Cells Direct Significant Rhinovirus Replication in Monocytic Cells by Enhancing ICAM1 Expression. Am J Respir Cell Mol Biol. 2017;57(2):216-225.

Zhu H, Kwak HJ, Liu P, Bajrami B, Xu Y, Park SY, Nombela-Arrieta C, Mondal S, Kambara H, Yu H, Chai L, Silberstein LE, Cheng T, Luo HR. Reactive Oxygen Species-Producing Myeloid Cells Act as a Bone Marrow Niche for Sterile Inflammation-Induced Reactive Granulopoiesis. J Immunol. 2017;198(7):2854-2864.

Zucconi BE, Cole PA. Allosteric regulation of epigenetic modifying enzymes. Curr Opin Chem Biol. 2017;39:109-115.

Presentations and Abstracts 2017

Barrero CA. Histone H3.3: A novel pharmaceutical target for the treatment of COPD. Presentede at Pharmaceutical Science Department, Temple University School of Pharmacy. Philadelphia, PA, May 30, 2017.

Che P, Zhao X, Cai G, Hu M, Chen CY, Han X, Ding Q. Tristetraprolin regulates cigarette smoke induced TNF-alpha expression through an mRNA decay mechanism [abstract]. American Thoracic Society International Conference. Washington, DC, May 19-24, 2017.

Che P, Zhao X, Cai G, Hu M, Zhou Y, Thannickal VJ, Olman M, Ding Q, FAK-related non-kinase regulates lung fibrosis through inhibition of metabolic reprograming [abstract]. American Thoracic Society International Conference. Washington, DC, May 19-24, 2017.

Clerkin CG, Matzinger M, Selo MA, Talbot BN, Walsh JJ, Ehrhardt C. Aromatic substitution reaction of ergothioneine – a novel mechanism of xenobiotic deactivation [abstract]. FASEB J 2017 31:821.1.

Collaco, M. Current use and exposure of e-cigarettes among pediatric populations. Presented at the plenary session, 21st Congress of the International Society for Aerosols in Medicine. Santa Fe, NM, Jun 3-7, 2017.

Cummings, KM. 50-year Surgeon General Report. Presented at the 21st Annual Family Medicine Update: Tobacco & Disease Pre-Conf. Little Rock, AR, Oct 2017.

Cummings, KM. Framework Convention on Tobacco Control (FCTC). Presented at the APHA Annual meeting. Atlanta, GA, Nov 2017.

Cummings, KM. Framework Convention on Tobacco Control (FCTC). Presented at the IASLC 18th World Conference on Lung Cancer. Yokohama, Japan, Oct 2017.

Cummings, KM. Framework Convention on Tobacco Control (FCTC). Presented at the APHA Annual Meeting. Atlanta, GA, Nov 2017.

Cummings, KM. The Evolving Cigarette. Presented at the 22nd Century Shareholder’s Meeting. Buffalo, NY, Apr 2017.

Cummings, KM. The Evolving Cigarette. Presented at the AAMC Lung Health Awareness Event, Anne Arundel Medical Center. Annapolis, MD, Nov 2017.

Cummings, KM. The Evolving Cigarette. Presented at the American Society for Preventive Cardiology’s 2017 Congress on CVD Prevention. Fort Lauderdale, FL, Sep 2017.

Cummings, KM. The Evolving Cigarette. Presented at the FSU College of Medicine CTTS Recertification Conference. Jacksonville, FL, May 2017.

Cummings, KM. The Evolving Cigarette. Presented at the IASLC 17th Annual Targeted Therapies of Lung Cancer. Santa Monica, CA, Feb 2017.

Cummings, KM. The Evolving Cigarette. Presented at the MT Public Health Association Annual Conference. Missoula, MT, Sep 2017.

Cummings, KM. The Evolving Cigarette. Presented at the MultiCare Health System Great American Smokeout Event. Tacoma, WA, Nov 2017.

Cummings, KM. The Evolving Cigarette. Presented at the NCTOH Annual Meeting. Austin, TX, Mar 2017.

Cummings, KM. The Evolving Cigarette. Presented at the Say What! Texas Tobacco-Free Conference. San Marcos, TX, Jul 2017.

Cummings, KM. The Evolving Cigarette. Presented at the South Carolina Tobacco-Free Collaborative Annual Meeting. Columbia, SC, Jan 2017.

Cummings, KM. The Evolving Cigarette. Presented at the The E-Cigarette Summit – Science, Regulation and Public Health. Washington, DC, May 2017.

Cummings, KM. The Evolving Cigarette. Presented at the University of Arkansas at Pine Bluff. Pine Bluff, AK, May 2017.

Cummings, KM. Towards Health Through Justice. Presented at the 34th Annual Judges & Attorneys Substance Abuse & Ethics Seminar. Daniel Island, SC, Dec 2017.

Cummings, KM. Towards Health Through Justice. Presented at the IASLC 18th World Conference on Lung Cancer. Yokohama, Japan, Oct 2017.

Cummings, KM. Towards Health Through Justice. Presented at the NCTOH Annual Meeting. Austin, TX, Mar 2017.

Dalanhese D, Winden D, Bikman B, Arroyo J, Reynolds P, Roberts D, Vanmali S, Peterson M, Jacobsen C, Sarva S, Hirschi K, Lewis J, Wilcox S.  Gingival cells exposed to e-cigarette liquid induce pro-inflammatory cytokine elaboration. Presented at the AADR Annual Meeting. San Francisco, CA, Mar 25, 2017.

Ehrhardt C. Determination of expression and activity of breast cancer resistance protein (BCRP/ABCG2) in human lung alveolar epithelial barrier in vitro. Presented at the 21st Congress of the International Society for Aerosols in Medicine. Santa Fe, NM, Jun 5, 2017.

Ehrhardt C. Ergothioneine, OCTN1 and COPD. Presented at the Western Epithelial Biology Society Meeting. Avila Beach, CA, Mar 4, 2017.

Frank DN. Understanding and manipulating the microbiome. Presented at the FAMRI Sinusitis Meeting. Miami, FL, Feb 2, 2017.

Gamliel VM, Shilo S, Rosen L. Parental perceptions of exposure – a new tool to examine parental understanding of children’s exposure to tobacco smoke:  A validation study. Presented at the Tel Aviv University Medical Faculty Research Fair. Tel Aviv, Israel, 2017.

Garcia-Arcos I, Alvarez-Buve R, Chow L, Goldberg IJ, Foronjy RF. Deletion of LRP1 in Airway epithelium exacerbates smoke-induced oxidative damage [abstract]. Circulation 2017;136:A19423.

Guerrero-Plata A, Cheemarla N. In utero tobacco smoke exposure suppresses the PRR expression in response to virus infection. Presented at the Keystone Symposium. Banff, Alberta, Canada, Mar 19–23, 2017.

Gorzkowski J, Wheeler G, Houston T, Williams J, Bornstein S, Phelan S, Klein J. Health systems transformation to increase tobacco cessation: the physician perspective. Presented at the National Conference on Tobacco or Health. Austin TX, Mar 22-24, 2017.

Gorzkowski J. Updates from the AAP Richmond Center and Section on Tobacco Control. Presented at the Pediatric Tobacco Issues Special Interest Group at the 2017 Pediatric Academic Societies Annual Conference. San Francisco, CA, May 2017.

Gorzkowski JA, Kaseeska KR, Wright M, Harris D, Shone L, Whitmore R, Klein J. Implementation and impact of the 5As tobacco counseling intervention with adolescents in pediatric practice. Presented at the National Conference on Tobacco or Health. Austin TX, Mar 22-24, 2017.

Gregory AD, Agostini BA, Chu Y, Zhang Y, Shapiro SD.  Effects of insulin-like growth factor signaling pathways on the development of emphysema {abstract].  Am J Respir Crit Care Med 2017;195:A7371.

Groner J. Electronic Cigarettes and Vaping—What you and your patients don’t know can hurt them. Presented at the Science Symposium, Pediatric Academic Societies annual meeting. San Francisco, CA, May 6-9, 2017.

Groner JA, Huang H, Nicholson L, Bauer, JA. Secondhand smoke exposure and pre-clinical cardiovascular risk in toddlers. Presented at the Pediatric Academic Societies annual meeting. San Francisco, CA, May 6-9, 2017.

Harris C, Buffington A, McMillen R. State-wide tobacco reporting and progress system (TRAPS). Presented at the National Conference on Tobacco or Health. Austin TX, Mar 22-24, 2017.

Hirschi KM, Lewis JB, Hall PD, Wright TJ, Egbert KM, Ogden KC, Nelson SM, Clark JC, Milner DC, Arroyo JA, Reynolds PR. Abrogation of RAGE signaling using semi-synthetic glycosaminoglycan ethers (SAGEs) ameliorates inflammation in mice exposed to secondhand tobacco smoke. FASEB J 2017;31:656.1.

Hirschi KM, Lewis JB, Ostergar AS, Hall PD, Broberg DS, Arroyo JA, Reynolds PR. Involvement of RAGE signaling and inflammatory cytokine elaboration following in vitro exposure to electronic cigarette liquid. FASEB J 2017 31:657.6.

Hosakote YM, Rayavara K, Xu B, Luo X, Wu Z, Kurosky A. Respiratory syncytial virus infection modulates nuclear protein HMGB1 for its extracellular release to promote inflammatory response. 8th International DAMPs and Alarmins Symposium (iDEAs). Presented at the Feinstein Institute for Medical Research and Cold Spring Harbor Laboratory. Cold Spring Harbor, NY, Nov 6-7, 2017.

Ji X, Qian J, Zou Y, Rahman J, Harris B, Hoeksema M, Eisenberg R, Young H, Chen H, Massion PP. xCT induces tumorigenesis in non-small cell lung cancer by activation of cMyc pathway. Presented at the VICC Cancer Metabolism Retreat. Nashville, TN, May 4, 2017.

Klein J, Gorzkowski J, Wilson K, Tanski S, Tait V. Strengthening tobacco control capacity in global settings: engaging child health leaders [abstract]. Presented at the 144th Annual Conference of the American Public Health Association. Atlanta, GA, Nov 10-14, 2017.

Klein, J. Children and Tobacco 2017: Who is winning? Visiting Professorship presentation at UCSF-San Francisco General Hospital. San Francisco, CA, Nov 2017.

Klein, J. Product preferences among light and regular adolescent e-cigarette users: results from the first waves of the PATH Study [abstract]. Presented at the Robert Wood Johnson National Clinical Scholars Program Annual Meeting. New Haven, CT, Nov 2017.

Kovacs L, Cai P, Su Y. Inhibitory role of BMP4 on the PDGF-induced proliferation and collagen synthesis in PASMCs. FASEB J 2017;31(1)Suppl lb653.

Krick S, Sailland-Tschudi J, Grosche A, Baumlin N, Salathe M. Effect of fibroblast growth factor signaling on mucociliary function in cystic fibrosis. Presented at the North American Cystic Fibrosis Conference. Indianapolis, IN, Nov 2-4, 2017.

Krick S, Sailland-Tschudi J, Martin S, Kuenzi L, Dennnis JS, Baeumlin N, Grabner A, Faul C, Salathe M. klotho increases airway surface liquid volume in human bronchial epithelial cells [abstract]. Am J Respir Crit Care Med 2017;195:A435.

Layec G. Physiological factors contributing to the age-related decline in walking speed & prospective counter-measures. Presented at the Geriatric Research Conference, University of Utah. Salt Lake City, UT, Apr 11, 2017.

Lewis JB, Mejia CA, Jordan C, Monson TD, Bodine JS, Dunaway TM, Egbert KM, Wright TJ, Ogden KC, Broberg DS, Hall PD, Nelson SM, Hirschi KM, Reynolds PR, and Arroyo JA. Inhibition of the Receptor for Advanced Glycation End-products (RAGE) protects from secondhand smoke (SHS) induced intrauterine growth restriction (IUGR) in mice.  FASEB J 2017; 31(1) Supplement.

McClelland E, McMillen R, Huell, Bryant J. Social Climate Survey of Tobacco Control: Identifying support for tobacco control policies in Mississippi. Presented at the National Conference of Tobacco or Health. Austin, TX, Mar 22-24, 2017.

McMillen R, McClelland E, Valentine N. Surveillance informing policy and practice. Presented at the National Conference of Tobacco or Health. Austin TX, Mar 22-24, 2017.

McMillen R, Tanski S, Wilson K, Klein J, Winickoff J. Product preferences among light and regular adolescent e-cigarette users: results from the first waves of the PATH study. Presented at the 144th Annual Conference of the American Public Health Association. Atlanta, GA, Nov 10-14, 2017.

McMillen R, Wilson K, Tanski S, Klein JD, Winickoff JP. US adult attitudes and practices about smoking restrictions and child exposure to tobacco smoke, 2000-2015. Presented at the Pediatric Academic Societies’ Annual Conference. San Francisco, CA, May 6-9, 2017.

McMillen, R. Using databases in tobacco research. Presented at the Pediatric Tobacco Issues Special Interest Group at the 2017 Pediatric Academic Societies Annual Conference. San Francisco, CA, May, 2017.

Myers V, Shiloh S, Rosen L. Development of a tool to assess parental perceptions of exposure to tobacco smoke. Presented at the Annual Conference of Public Health Physicians and Schools of Public Health. Ramat Gan, Israel, Jun 5, 2017.

Nardone N, Jain S, Dempsey D, Jacob P, Benowitz NL. Secondhand smoke exposure among a vulnerable population of adolescents. Presented at the 23rd Annual Society for Research on Nicotine & Tobacco Conference. Florence, Italy, Mar 8-11, 2017.

Puthusseri B, Marudamuthu A, Tiwari N, Gopu V, Fu J, Idell S, Shetty S. Regulation of p53-mediated changes in the uPA-fibrinolytic system and in lung injury by loss of surfactant protein-C expression in alveolar epithelial cells [abstract]. American Thoracic Society International Conference. Washington, DC, May 19-24, 2017.

Radder JE, Gregory AD, Chu Y, Zhang Y, Shapiro SD.  IL-1 signaling imbalance affects lung development and predisposes to cigarette smoke-induced emphysema in mice. [abstract]  Am J Respir Crit Care Med 2017;195:A7367.

Rayavara K, Stafford S, Kurosky A, Hosakote YM. Respiratory syncytial virus-induced epithelial HMGB1 release activates immune cells to promote inflammatory response. Presnted at the 8th International DAMPs and Alarmins Symposium (iDEAs). The Feinstein Institute for Medical Research and Cold Spring Harbor Laboratory. Cold Spring Harbor, NY, Nov 6-7, 2017.

Reynolds PR. Cigarette smoke extract increases RAGE signaling and invasion in Ca9-22 gingival cancer cells. Presented at the American Association for Dental Research Meeting. San Francisco, CA, Mar 22-25, 2017.

Reynolds PR. Semi-synthetic glycosaminoglycan ethers inhibit cell invasion induced by CSE. Presented at the American Association for Dental Research Meeting. San Francisco, CA, Mar 22-25, 2017.

Rosen L, Lev E, Guttman N, Tillinger E, Rosenblat S, Zucker D, Myers V.  “I’m not smoking at home, I’m smoking in the window”: Perceptions, misconceptions, and parental behavior regarding child tobacco smoke exposure. Presented at the Annual Conference of Public Health Physicians and Schools of Public Health. Ramat Gan, Israel, 2017.

Rosen L, Myers V, Guttman N, Shilo S. Berkovitch M, Braun N, Aperman T, Theitler N, Zucker D. An intervention to protect young children from tobacco smoke exposure: Interim report of a randomized controlled trial. Presented at the Annual Conference of Public Health Physicians and Schools of Public Health. Ramat Gan, Israel, Jun 5, 2017.

Sailland-Tschudi J, Grosche A, Baumlin-Schmid N, Dennis JS, Schmid A, Krick S, Salathe M. Smad3 and P38 pathways mediate cigarette smoke-induced decreases in CFTR and BK channel activities leading to mucociliary dysfunction. Am J Respir Crit Care Med 2017;195:A6270.

Sarva S, Winden D, Bikman B, Arroyo J, Reynolds P, Vanmali S, Dalanhese D, Roberts D, Peterson M, Jacobsen C, Hirschi K, Lewis J, Wilcox S.  Gingival Cells Exposed to e-cigarette liquid express differential recognition receptors.  Presented at the AADR Annual Meeting. San Francisco, CA, Mar 22, 2017.

Selo MA, Nickel S, Clerkin CG, Ehrhardt C. Ergothioneine induces antioxidant enzymes in human lung epithelial cells in vitro [abstract]. Am J Respir Crit Care Med 2017;195:A6279.

Shetty SK, Tiwari N, Marudamuthu A, Puthusseri B, Bhandary YP, Fu J, Levin J, Idell S, Shetty S. p53 and microRNA-34a feedback promotes lung epithelial injury and remodeling [abstract]. American Thoracic Society International Conference. Washington, DC, May 19-24, 2017.

Tanski, S. Adolescent substance use: screening, brief intervention and referral to treatment. Presented at the 27th Dartmouth Pediatric Conference: Contemporary Issues in Office Pediatrics. Bretton Woods, NH, 2017.

Tanski, S. Vaping, puffing and dripping, oh my! Presented at the Primary Care Associate Provider Quarterly Education Conference. Dartmouth Hitchcock Medical Center, Lebanon, NH, 2017.

Torok MR, Lowary M, Kerby G, Hovell M, Winickoff J, Klein J, Wilson KM. Parental beliefs and behaviors about protecting children from tobacco smoke. Presented at the Pediatric Academic Societies meeting. San Francisco, CA, May 6-9, 2017.

Torok MR, Lowary M, Rohde J, Kerby G, Hovell M, Winickoff J, Klein J, Wilson KM. Comfort in talking with patients/families about smoking tobacco among employees of a children’s hospital before and during a tobacco cessation study. Presented at the Pediatric Academic Societies meeting. San Francisco, CA, May 6-9, 2017.

Valentine N, McMillen R, Changing tobacco trends in Mississippi. Presented at the National Conference of Tobacco or Health. Austin, TX, Mar 22-24, 2017.

Wei B, Wang L, Blount B, Wilson K, Torok M, Lowary M. Marijuana smoke exposure among hospitalized children exposed to tobacco smoke. Presented at the Pediatric Academic Societies meeting. San Francisco, CA, May 6-9, 2017.

Willis A, Moss A, Torok MR, Robinson M, Wilson KM. Marijuana smoke exposure and cytokine prevalence in hospitalized children. Presented at the Pediatric Hospital Medicine Annual Conference. Chicago, IL, Jul 28-31, 2016.

Wilson, K. No ENDS in sight: addressing e-cigarettes and vaping in your practice. Presented at the 2018 AAP National Conference and Exhibition. Chicago IL, Sep 16-19, 2017.

Winickoff, J. The clinical effort against secondhand smoke exposure (CEASE): strategies to help families become tobacco-free. Hong Kong University campus-wide lecture. Hong Kong, China, Nov 2017.

Winickoff, J. Thirdhand smoke and tobacco 21: two important end game strategies. Presented at the International Press Conference sponsored by Hong Kong Department of Health. Hong Kong, China, Dec 2017.

Winickoff, J. Thirdhand smoke and tobacco 21: two important end game strategies. Presented at the Plenary Session, 35th Anniversary of Smokefree Hong Kong Conference. Department of Public Health and Committee on Smoking and Health. Hong Kong, China, Dec 1, 2017.

Wu BG, Li Y, Wang J, Clemente J, Zangari T, Weiser JN, Segal LN. Microaspiration murine model with non-pathogenic S. Pneumoniae results in “like will to like” microbiota phenomenon [abstract]. Am J Respir Crit Care Med 2017;195:A1006.

Xiao R, Wu BG, Goldklang M, McClelland M, Segal LN, D’Armiento JM. Cigarette smoke dysregulates gut microbiome in multiple strains of mice correlating with inflammation in the lung [abstract]. Am J Respir Cell Mol Biol 2017;195:A1006.

Book Chapters, etc., 2017

Baker T, Lee PJ, Sauler M. MIF and pulmonary disease, In: MIF Family Cytokines in Innate Immunity and Homeostasis, Bucala R, Bernhagen J, eds. Springer 2017.

Cummings M., Brown A, The Evolving Cigarette Exhibit Link:  https://vimeo.com/204831249 2017.

Hage P, Brown A, Cummings KM, Poole T. The Evolving Cigarette. (2017) Buffalo, NY: Roswell Park Cancer Institute. DVD and Online. Link – https://vimeo.com/194709338 2017.

Raju SV, Rasmussen L: UAB Research Foundation, “Method and composition for increasing mucus clearance”. PCT/US2017/054405.  World Intellectual Property Organization- International Publication Number: WO 2018/064529 A1, 2017.