Flight Attendant Medical Research Institute Publications and Presentations: 2018

Publications and Presentations: 2018

Abdullah AS, Guangmin N, Kaiyong H, Jing L, Yang L, Zhang Z, Winickoff JP. Implementing Tobacco Control Assistance in Pediatric Departments of Chinese Hospitals: A Feasibility Study. Pediatrics. 2018;141(Suppl 1):S51-S62.

Aloni-Grinstein R, Charni-Natan M, Solomon H, Rotter V. p53 and the Viral Connection: Back into the Future (double dagger). Cancers (Basel). 2018;10(6).

Alt JA, Lee WY, Davis BM, Savage JR, Kennedy TP, Prestwich GD, Pulsipher A. A synthetic glycosaminoglycan reduces sinonasal inflammation in a murine model of chronic rhinosinusitis. PLoS One. 2018;13(9):e0204709.

Amariei DE, Reed RM. Troubleshooting a dialysis line: when blue runs red. BMJ Case Rep. 2018;2018.

Arjomandi M, Zeng S, Geerts J, Stiner RK, Bos B, van Koeverden I, Keene J, Elicker B, Blanc PD, Gold WM. Lung volumes identify an at-risk group in persons with prolonged secondhand tobacco smoke exposure but without overt airflow obstruction. BMJ Open Respir Res. 2018;5(1):e000284.

Babu N, Advani J, Solanki HS, Patel K, Jain A, Khan AA, Radhakrishnan A, Sahasrabuddhe NA, Mathur PP, Nair B, Keshava Prasad TS, Chang X, Sidransky D, Gowda H, Chatterjee A. miRNA and Proteomic Dysregulation in Non-Small Cell Lung Cancer in Response to Cigarette Smoke. Microrna. 2018;7(1):38-53.

Banos-Lara MDR, Zabaleta J, Garai J, Baddoo M, Guerrero-Plata A. Comparative analysis of miRNA profile in human dendritic cells infected with respiratory syncytial virus and human metapneumovirus. BMC Res Notes. 2018;11(1):432.

Bauer L, Ferla S, Head SA, Bhat S, Pasunooti KK, Shi WQ, Albulescu L, Liu JO, Brancale A, van Kuppeveld FJM, Strating J. Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP). Antiviral Res. 2018;156:55-63.

Belsky JB, Rivers EP, Filbin MR, Lee PJ, Morris DC. Thymosin beta 4 regulation of actin in sepsis. Expert Opin Biol Ther. 2018;18(sup1):193-197.

Benitez A, Liu W, Palovcak A, Wang G, Moon J, An K, Kim A, Zheng K, Zhang Y, Bai F, Mazin AV, Pei XH, Yuan F, Zhang Y. FANCA Promotes DNA Double-Strand Break Repair by Catalyzing Single-Strand Annealing and Strand Exchange. Mol Cell. 2018;71(4):621-628 e624.

Benowitz NL, Nardone N, Jain S, Dempsey DA, Addo N, St Helen G, Jacob P, 3rd. Comparison of Urine 4-(Methylnitrosamino)-1-(3)Pyridyl-1-Butanol and Cotinine for Assessment of Active and Passive Smoke Exposure in Urban Adolescents. Cancer Epidemiol Biomarkers Prev. 2018;27(3):254-261.

Berg OK, Kwon OS, Hureau TJ, Clifton HL, Thurston T, Le Fur Y, Jeong EK, Amann M, Richardson RS, Trinity JD, Wang E, Layec G. Maximal strength training increases muscle force generating capacity and the anaerobic ATP synthesis flux without altering the cost of contraction in elderly. Exp Gerontol. 2018;111:154-161.

Bhat S, Hwang Y, Gibson MD, Morgan MT, Taverna SD, Zhao Y, Wolberger C, Poirier MG, Cole PA. Hydrazide Mimics for Protein Lysine Acylation To Assess Nucleosome Dynamics and Deubiquitinase Action. J Am Chem Soc. 2018;140(30):9478-9485.

Bhat TA, Kalathil SG, Bogner PN, Miller A, Lehmann PV, Thatcher TH, Phipps RP, Sime PJ, Thanavala Y. Secondhand Smoke Induces Inflammation and Impairs Immunity to Respiratory Infections. J Immunol. 2018;200(8):2927-2940.

Blagev DP, Collingridge DS, Rea S, Horne BD, Press VG, Churpek MM, Carey KA, Mularski RA, Zeng S, Arjomandi M. The Laboratory-Based Intermountain Validated Exacerbation (LIVE) Score Identifies Chronic Obstructive Pulmonary Disease Patients at High Mortality Risk. Front Med (Lausanne). 2018;5:173.

Blagev DP, Collingridge DS, Rea S, Press VG, Churpek MM, Carey K, Mularski RA, Zeng S, Arjomandi M. Stability of Frequency of Severe Chronic Obstructive Pulmonary Disease Exacerbations and Health Care Utilization in Clinical Populations. Chronic Obstr Pulm Dis. 2018;5(3):208-220.

Boukhenouna S, Wilson MA, Bahmed K, Kosmider B. Reactive Oxygen Species in Chronic Obstructive Pulmonary Disease. Oxid Med Cell Longev. 2018;2018:5730395.

Breathett K, Liu WG, Allen LA, Daugherty SL, Blair IV, Jones J, Grunwald GK, Moss M, Kiser TH, Burnham E, Vandivier RW, Clark BJ, Lewis EF, Mazimba S, Battaglia C, Ho PM, Peterson PN. African Americans Are Less Likely to Receive Care by a Cardiologist During an Intensive Care Unit Admission for Heart Failure. JACC Heart Fail. 2018;6(5):413-420.

Broxterman RM, Hureau TJ, Layec G, Morgan DE, Bledsoe AD, Jessop JE, Amann M, Richardson RS. Influence of group III/IV muscle afferents on small muscle mass exercise performance: a bioenergetics perspective. J Physiol. 2018;596(12):2301-2314.

Cabrera Lopez C, Casanova Macario C, Marin Trigo JM, de-Torres JP, Sicilia Torres R, Gonzalez JM, Polverino F, Divo M, Pinto Plata V, Zulueta JJ, Celli B. Comparison of the 2017 and 2015 Global Initiative for Chronic Obstructive Lung Disease Reports. Impact on Grouping and Outcomes. Am J Respir Crit Care Med. 2018;197(4):463-469.

Carson JL, Hernandez M, Jaspers I, Mills K, Brighton L, Zhou H, Zhang J, Hazucha MJ. Interleukin-13 stimulates production of nitric oxide in cultured human nasal epithelium. In Vitro Cell Dev Biol Anim. 2018;54(3):200-204.

Chapman S, Mick M, Hall P, Mejia C, Sue S, Abdul Wase B, Nguyen MA, Whisenant EC, Wilcox SH, Winden D, Reynolds PR, Arroyo JA. Cigarette smoke extract induces oral squamous cell carcinoma cell invasion in a receptor for advanced glycation end-products-dependent manner. Eur J Oral Sci. 2018;126(1):33-40.

Charni-Natan M, Solomon H, Molchadsky A, Jacob-Berger A, Goldfinger N, Rotter V. Various stress stimuli rewire the profile of liver secretome in a p53-dependent manner. Cell Death Dis. 2018;9(6):647.

Cheemarla NR, Guerrero-Plata A. How does the human metapneumovirus regulate neutrophil infiltration into the airways? Future Virol. 2018;13(4):233-235.

Chen C, Deslouches B, Montelaro RC, Di YP. Enhanced efficacy of the engineered antimicrobial peptide WLBU2 via direct airway delivery in a murine model of Pseudomonas aeruginosa pneumonia. Clin Microbiol Infect. 2018;24(5):547 e541-547 e548.

Choi EJ, Ren Y, Chen Y, Liu S, Wu W, Ren J, Wang P, Garofalo RP, Zhou J, Bao X. Exchange Proteins Directly Activated by cAMP and Their Roles in Respiratory Syncytial Virus Infection. J Virol. 2018;92(22).

Choi J, Indrisiunaite G, DeMirci H, Ieong KW, Wang J, Petrov A, Prabhakar A, Rechavi G, Dominissini D, He C, Ehrenberg M, Puglisi JD. 2′-O-methylation in mRNA disrupts tRNA decoding during translation elongation. Nat Struct Mol Biol. 2018;25(3):208-216.

Chu N, Salguero AL, Liu AZ, Chen Z, Dempsey DR, Ficarro SB, Alexander WM, Marto JA, Li Y, Amzel LM, Gabelli SB, Cole PA. Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis. Cell. 2018;174(4):897-907 e814.

Collaco JM, McGrath-Morrow SA. Electronic Cigarettes: Exposure and Use Among Pediatric Populations. J Aerosol Med Pulm Drug Deliv. 2018;31(2):71-77.

De Benedetto F, Pastorelli R, Ferrario M, de Blasio F, Marinari S, Brunelli L, Wouters EFM, Polverino F, Celli BR, Interdisciplinary Association for Research in Lung Disease Study G. Supplementation with Qter[1]R and Creatine improves functional performance in COPD patients on long term oxygen therapy. Respir Med. 2018;142:86-93.

de la Hoz RE, Liu X, Doucette JT, Reeves AP, Bienenfeld LA, Wisnivesky JP, Celedon JC, Lynch DA, San Jose Estepar R. Increased Airway Wall Thickness is Associated with Adverse Longitudinal First-Second Forced Expiratory Volume Trajectories of Former World Trade Center workers. Lung. 2018;196(4):481-489.

Divo MJ, Celli BR, Poblador-Plou B, Calderon-Larranaga A, de-Torres JP, Gimeno-Feliu LA, Berto J, Zulueta JJ, Casanova C, Pinto-Plata VM, Cabrera-Lopez C, Polverino F, Carmona Pirez J, Prados-Torres A, Marin JM, EpiChron BCG. Chronic Obstructive Pulmonary Disease (COPD) as a disease of early aging: Evidence from the EpiChron Cohort. PLoS One. 2018;13(2):e0193143.

Elf JL, Kinikar A, Khadse S, Mave V, Gupte N, Kulkarni V, Patekar S, Raichur P, Cohen J, Breysse PN, Gupta A, Golub JE. Secondhand Smoke Exposure and Validity of Self-Report in Low-Income Women and Children in India. Pediatrics. 2018;141(Suppl 1):S118-S129.

Engel M, Eggert C, Kaplick PM, Eder M, Roh S, Tietze L, Namendorf C, Arloth J, Weber P, Rex-Haffner M, Geula S, Jakovcevski M, Hanna JH, Leshkowitz D, Uhr M, Wotjak CT, Schmidt MV, Deussing JM, Binder EB, Chen A. The Role of m(6)A/m-RNA Methylation in Stress Response Regulation. Neuron. 2018;99(2):389-403 e389.

Ezegbunam W, Foronjy R. Posttranscriptional control of airway inflammation. Wiley Interdiscip Rev RNA. 2018;9(1).

Feigelson SW, Solomon A, Biram A, Hatzav M, Lichtenstein M, Regev O, Kozlovski S, Varol D, Curato C, Leshkowitz D, Jung S, Shulman Z, Alon R. ICAMs Are Not Obligatory for Functional Immune Synapses between Naive CD4 T Cells and Lymph Node DCs. Cell Rep. 2018;22(4):849-859.

Florence JM, Krupa A, Booshehri LM, Gajewski AL, Kurdowska AK. Disrupting the Btk Pathway Suppresses COPD-Like Lung Alterations in Atherosclerosis Prone ApoE(-/-) Mice Following Regular Exposure to Cigarette Smoke. Int J Mol Sci. 2018;19(2).

Flores RM, Yankelevitz DF. Lung Cancer Screening: The True Benefit. Ann Thorac Surg. 2018;106(2):319-320.

Galanos P, Pappas G, Polyzos A, Kotsinas A, Svolaki I, Giakoumakis NN, Glytsou C, Pateras IS, Swain U, Souliotis VL, Georgakilas AG, Geacintov N, Scorrano L, Lukas C, Lukas J, Livneh Z, Lygerou Z, Chowdhury D, Sorensen CS, Bartek J, Gorgoulis VG. Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability. Genome Biol. 2018;19(1):37.

Gamliel M, Goldman-Wohl D, Isaacson B, Gur C, Stein N, Yamin R, Berger M, Grunewald M, Keshet E, Rais Y, Bornstein C, David E, Jelinski A, Eisenberg I, Greenfield C, Ben-David A, Imbar T, Gilad R, Haimov-Kochman R, Mankuta D, Elami-Suzin M, Amit I, Hanna JH, Yagel S, Mandelboim O. Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies. Immunity. 2018;48(5):951-962 e955.

Garth J, Barnes JW, Krick S. Targeting Cytokines as Evolving Treatment Strategies in Chronic Inflammatory Airway Diseases. Int J Mol Sci. 2018;19(11).

Ghosh M, Miller YE, Nakachi I, Kwon JB, Baron AE, Brantley AE, Merrick DT, Franklin WA, Keith RL, Vandivier RW. Exhaustion of Airway Basal Progenitor Cells in Early and Established Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018;197(7):885-896.

Ghosh M, Miller YE, Vandivier RW, all a. Reply to Sohal: Airway Basal Cell Reprogramming and Epithelial-Mesenchymal Transition: A Potential Key to Understanding Early Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018;197(12):1645-1646.

Gifford JR, Trinity JD, Kwon OS, Layec G, Garten RS, Park SY, Nelson AD, Richardson RS. Altered skeletal muscle mitochondrial phenotype in COPD: disease vs. disuse. J Appl Physiol (1985). 2018;124(4):1045-1053.

Glick DR, Motta M, Wiegand DL, Range P, Reed RM, Verceles AC, Shah NG, Netzer G. Anticipatory grief and impaired problem solving among surrogate decision makers of critically ill patients: A cross-sectional study. Intensive Crit Care Nurs. 2018;49:1-5.

Gonzalez-Gil A, Porell RN, Fernandes SM, Wei Y, Yu H, Carroll DJ, McBride R, Paulson JC, Tiemeyer M, Aoki K, Bochner BS, Schnaar RL. Sialylated keratan sulfate proteoglycans are Siglec-8 ligands in human airways. Glycobiology. 2018;28(10):786-801.

Gorzkowski JA, Klein JD. The Role of Secondhand Smoke Research in Protecting Nonsmokers. Pediatrics. 2018;141(Suppl 1):S6-S9.

Gour N, Sudini K, Khalil SM, Rule AM, Lees P, Gabrielson E, Groopman JD, Lajoie S, Singh A. Unique pulmonary immunotoxicological effects of urban PM are not recapitulated solely by carbon black, diesel exhaust or coal fly ash. Environ Res. 2018;161:304-313.

Groner JA, Rule AM, McGrath-Morrow SA, Collaco JM, Moss A, Tanski SE, McMillen R, Whitmore RM, Klein JD, Winickoff JP, Wilson K. Assessing pediatric tobacco exposure using parent report: comparison with hair nicotine. J Expo Sci Environ Epidemiol. 2018;28(6):530-537.

Hart CR, Layec G, Trinity JD, Kwon OS, Zhao J, Reese VR, Gifford JR, Richardson RS. Increased skeletal muscle mitochondrial free radical production in peripheral arterial disease despite preserved mitochondrial respiratory capacity. Exp Physiol. 2018;103(6):838-850.

Hart CR, Layec G, Trinity JD, Le Fur Y, Gifford JR, Clifton HL, Richardson RS. Oxygen availability and skeletal muscle oxidative capacity in patients with peripheral artery disease: implications from in vivo and in vitro assessments. Am J Physiol Heart Circ Physiol. 2018;315(4):H897-H909.

Heerma van Voss MR, Vesuna F, Bol GM, Afzal J, Tantravedi S, Bergman Y, Kammers K, Lehar M, Malek R, Ballew M, Ter Hoeve N, Abou D, Thorek D, Berlinicke C, Yazdankhah M, Sinha D, Le A, Abrahams R, Tran PT, van Diest PJ, Raman V. Targeting mitochondrial translation by inhibiting DDX3: a novel radiosensitization strategy for cancer treatment. Oncogene. 2018;37(1):63-74.

Hengsawas Surasarang S, Florova G, Komissarov AA, Shetty S, Idell S, Williams RO, 3rd. Formulation for a novel inhaled peptide therapeutic for idiopathic pulmonary fibrosis. Drug Dev Ind Pharm. 2018;44(2):184-198.

Henschke CI, Salvatore M, Cham M, Powell CA, DiFabrizio L, Flores R, Kaufman A, Eber C, Yip R, Yankelevitz DF, International Early Lung Cancer Action Program I. Correction to: Baseline and annual repeat rounds of screening: implications for optimal regimens of screening. Eur Radiol. 2018;28(7):3114.

Henschke CI, Salvatore M, Cham M, Powell CA, DiFabrizio L, Flores R, Kaufman A, Eber C, Yip R, Yankelevitz DF, International Early Lung Cancer Action Program I. Baseline and annual repeat rounds of screening: implications for optimal regimens of screening. Eur Radiol. 2018;28(3):1085-1094.

Hirschi KM, Chapman S, Hall P, Ostergar A, Winden DR, Reynolds PR, Arroyo JA. Gas6 protein induces invasion and reduces inflammatory cytokines in oral squamous cell carcinoma. J Oral Pathol Med. 2018;47(8):748-754.

Hoti N, Johnson TJ, Chowdhury WH, Rodriguez R. Loss of Cyclin-Dependent Kinase Inhibitor Alters Oncolytic Adenovirus Replication and Promotes More Efficient Virus Production. Cancers (Basel). 2018;10(6).

Hou Q, Liu F, Chakraborty A, Jia Y, Prasad A, Yu H, Zhao L, Ye K, Snyder SH, Xu Y, Luo HR. Inhibition of IP6K1 suppresses neutrophil-mediated pulmonary damage in bacterial pneumonia. Sci Transl Med. 2018;10(435).

Hough KP, Wilson LS, Trevor JL, Strenkowski JG, Maina N, Kim YI, Spell ML, Wang Y, Chanda D, Dager JR, Sharma NS, Curtiss M, Antony VB, Dransfield MT, Chaplin DD, Steele C, Barnes S, Duncan SR, Prasain JK, Thannickal VJ, Deshane JS. Unique Lipid Signatures of Extracellular Vesicles from the Airways of Asthmatics. Sci Rep. 2018;8(1):10340.

Jacob-Hirsch J, Eyal E, Knisbacher BA, Roth J, Cesarkas K, Dor C, Farage-Barhom S, Kunik V, Simon AJ, Gal M, Yalon M, Moshitch-Moshkovitz S, Tearle R, Constantini S, Levanon EY, Amariglio N, Rechavi G. Whole-genome sequencing reveals principles of brain retrotransposition in neurodevelopmental disorders. Cell Res. 2018;28(2):187-203.

Ji X, Niu X, Qian J, Martucci V, Pendergrass SA, Gorlov IP, Amos CI, Denny JC, Massion PP, Aldrich MC. A Phenome-Wide Association Study Uncovers a Role for Autoimmunity in the Development of Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2018;58(6):777-779.

Ji X, Qian J, Rahman SMJ, Siska PJ, Zou Y, Harris BK, Hoeksema MD, Trenary IA, Heidi C, Eisenberg R, Rathmell JC, Young JD, Massion PP. xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression. Oncogene. 2018;37(36):5007-5019.

Jiang W, Zhou X, Li Z, Liu K, Wang W, Tan R, Cong X, Shan J, Zhan Y, Cui Z, Jiang L, Li Q, Shen S, Bai M, Cheng Y, Li B, Tan M, Ma DK, Liu JO, Dang Y. Prolyl 4-hydroxylase 2 promotes B-cell lymphoma progression via hydroxylation of Carabin. Blood. 2018;131(12):1325-1336.

Jin H, Ciechanowicz AK, Kaplan AR, Wang L, Zhang PX, Lu YC, Tobin RE, Tobin BA, Cohn L, Zeiss CJ, Lee PJ, Bruscia EM, Krause DS. Surfactant protein C dampens inflammation by decreasing JAK/STAT activation during lung repair. Am J Physiol Lung Cell Mol Physiol. 2018;314(5):L882-L892.

Jin M, Lee EC, Ra SW, Fishbane N, Tam S, Criner GJ, Woodruff PG, Lazarus SC, Albert R, Connett JE, Han MK, Martinez FJ, Aaron SD, Reed RM, Man SFP, Leung JM, Sin DD. Relationship of Absolute Telomere Length With Quality of Life, Exacerbations, and Mortality in COPD. Chest. 2018;154(2):266-273.

Jung EH, Meyers DJ, Bosch J, Casadevall A. Novel Antifungal Compounds Discovered in Medicines for Malaria Venture’s Malaria Box. mSphere. 2018;3(2).

Kalin JH, Wu M, Gomez AV, Song Y, Das J, Hayward D, Adejola N, Wu M, Panova I, Chung HJ, Kim E, Roberts HJ, Roberts JM, Prusevich P, Jeliazkov JR, Roy Burman SS, Fairall L, Milano C, Eroglu A, Proby CM, Dinkova-Kostova AT, Hancock WW, Gray JJ, Bradner JE, Valente S, Mai A, Anders NM, Rudek MA, Hu Y, Ryu B, Schwabe JWR, Mattevi A, Alani RM, Cole PA. Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors. Nat Commun. 2018;9(1):53.

Karzbrun E, Kshirsagar A, Cohen SR, Hanna JH, Reiner O. Human Brain Organoids on a Chip Reveal the Physics of Folding. Nat Phys. 2018;14(5):515-522.

Kaur G, Bagam P, Pinkston R, Singh DP, Batra S. Cigarette smoke-induced inflammation: NLRP10-mediated mechanisms. Toxicology. 2018;398-399:52-67.

Kaur G, Pinkston R, McLemore B, Dorsey WC, Batra S. Immunological and toxicological risk assessment of e-cigarettes. Eur Respir Rev. 2018;27(147).

Khan M, Khan Z, Uddin Y, Mustafa S, Shaukat I, Pan J, Hoti N. Evaluating the Oncogenic and Tumor Suppressor Role of XPO5 in Different Tissue Tumor Types. Asian Pac J Cancer Prev. 2018;19(4):1119-1125.

Kiser TH, Burnham EL, Clark B, Ho PM, Allen RR, Moss M, Vandivier RW. Half-Dose Versus Full-Dose Alteplase for Treatment of Pulmonary Embolism. Crit Care Med. 2018;46(10):1617-1625.

Klein JD. E-Cigarettes: A 1-Way Street to Traditional Smoking and Nicotine Addiction for Youth. Pediatrics. 2018;141(1).

Koifman G, Shetzer Y, Eizenberger S, Solomon H, Rotkopf R, Molchadsky A, Lonetto G, Goldfinger N, Rotter V. A Mutant p53-Dependent Embryonic Stem Cell Gene Signature Is Associated with Augmented Tumorigenesis of Stem Cells. Cancer Res. 2018;78(20):5833-5847.

Krick S, Grabner A, Baumlin N, Yanucil C, Helton S, Grosche A, Sailland J, Geraghty P, Viera L, Russell DW, Wells JM, Xu X, Gaggar A, Barnes J, King GD, Campos M, Faul C, Salathe M. Fibroblast growth factor 23 and Klotho contribute to airway inflammation. Eur Respir J. 2018;52(1).

Krick S, Helton ES, Hutcheson SB, Blumhof S, Garth JM, Denson RS, Zaharias RS, Wickham H, Barnes JW. FGF23 Induction of O-Linked N-Acetylglucosamine Regulates IL-6 Secretion in Human Bronchial Epithelial Cells. Front Endocrinol (Lausanne). 2018;9:708.

Kariano MC, Lin YT, Murnane M, Liu H, Smith GA, Wong SW, Taunton J, Liu JO, Mitsiades CS, Hann BC, Aftab BT, Wiita AP. Repurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment. Haematologica. 2018;103(7):1218-1228.

Laucho-Contreras ME, Polverino F, Rojas-Quintero J, Wang X, Owen CA. Club cell protein 16 (Cc16) deficiency increases inflamm-aging in the lungs of mice. Physiol Rep. 2018;6(15):e13797.

Layec G, Blain GM, Rossman MJ, Park SY, Hart CR, Trinity JD, Gifford JR, Sidhu SK, Weavil JC, Hureau TJ, Amann M, Richardson RS. Acute High-Intensity Exercise Impairs Skeletal Muscle Respiratory Capacity. Med Sci Sports Exerc. 2018;50(12):2409-2417.

Layec G, Trinity JD, Hart CR, Le Fur Y, Zhao J, Reese V, Jeong EK, Richardson RS. Impaired Muscle Efficiency but Preserved Peripheral Hemodynamics and Mitochondrial Function With Advancing Age: Evidence From Exercise in the Young, Old, and Oldest-Old. J Gerontol A Biol Sci Med Sci. 2018;73(10):1303-1312.

Leifheit-Nestler M, Richter B, Basaran M, Nespor J, Vogt I, Alesutan I, Voelkl J, Lang F, Heineke J, Krick S, Haffner D. Impact of Altered Mineral Metabolism on Pathological Cardiac Remodeling in Elevated Fibroblast Growth Factor 23. Front Endocrinol (Lausanne). 2018;9:333.

Leiter N, Motta M, Reed RM, Adeyeye T, Wiegand DL, Shah NG, Verceles AC, Netzer G. Numeracy and Interpretation of Prognostic Estimates in Intracerebral Hemorrhage Among Surrogate Decision Makers in the Neurologic ICU. Crit Care Med. 2018;46(2):264-271.

Lewis JB, Bodine JS, Gassman JR, Munoz SA, Milner DC, Dunaway TM, Egbert KM, Monson TD, Broberg DS, Arroyo JA, Reynolds PR. Transgenic up-regulation of Claudin-6 decreases fine diesel particulate matter (DPM)-induced pulmonary inflammation. Environ Sci Pollut Res Int. 2018;25(18):18179-18188.

Lewis JB, Jimenez FR, Merrell BJ, Kimbler B, Arroyo JA, Reynolds PR. The expression profile of Claudin family members in the developing mouse lung and expression alterations resulting from exposure to secondhand smoke (SHS). Exp Lung Res. 2018;44(1):13-24.

Li Y, Pasunooti KK, Li RJ, Liu W, Head SA, Shi WQ, Liu JO. Novel Tetrazole-Containing Analogues of Itraconazole as Potent Antiangiogenic Agents with Reduced Cytochrome P450 3A4 Inhibition. J Med Chem. 2018;61(24):11158-11168.

Liu S, Chen Y, Ren Y, Zhou J, Ren J, Lee I, Bao X. A tRNA-derived RNA Fragment Plays an Important Role in the Mechanism of Arsenite -induced Cellular Responses. Sci Rep. 2018;8(1):16838.

Liu Y, Yankelevitz DF, Kostakoglu L, Beasley MB, Htwe Y, Salvatore MM, Yip R, Henschke CI. Updating the role of FDG PET/CT for evaluation of lung cancer manifesting in nonsolid nodules. Clin Imaging. 2018;52:157-162.

Lyu J, Yang EJ, Head SA, Ai N, Zhang B, Wu C, Li RJ, Liu Y, Chakravarty H, Zhang S, Tam KY, Dang Y, Kwon HJ, Ge W, Liu JO, Shim JS. Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking. Int J Biol Sci. 2018;14(10):1175-1185.

Margolies LR, Salvatore M, Yip R, Tam K, Bertolini A, Henschke C, Yankelevitz D. The chest radiologist’s role in invasive breast cancer detection. Clin Imaging. 2018;50:13-19.

Marshall JD, Bazan I, Zhang Y, Fares WH, Lee PJ. Mitochondrial dysfunction and pulmonary hypertension: cause, effect, or both. Am J Physiol Lung Cell Mol Physiol. 2018;314(5):L782-L796.

McCormick LL, Phillips SE, Kaza N, Tang LP, Rasmussen L, Byzek SA, Raju SV, Rowe SM. Maternal Smoking Induces Acquired CFTR Dysfunction in Neonatal Rats. Am J Respir Crit Care Med. 2018;198(5):672-674.

McGrath-Morrow SA, Wilson KM. Editors’ Note. Pediatrics. 2018;141(Suppl 1):S3-S5.

McMillen R, Tanski S, Wilson K, Klein JD, Winickoff JP. Adolescent Use of Different E-cigarette Products. Pediatrics. 2018;142(4).

McMillen R, Wilson K, Tanski S, Klein JD, Winickoff JP. Adult Attitudes and Practices Regarding Smoking Restrictions and Child Tobacco Smoke Exposure: 2000 to 2015. Pediatrics. 2018;141(Suppl 1):S21-S29.

McNeely E, Mordukhovich I, Staffa S, Tideman S, Gale S, Coull B. Cancer prevalence among flight attendants compared to the general population. Environ Health. 2018;17(1):49.

McNeely E, Mordukhovich I, Tideman S, Gale S, Coull B. Estimating the health consequences of flight attendant work: comparing flight attendant health to the general population in a cross-sectional study. BMC Public Health. 2018;18(1):346.

McNeely E, Staffa SJ, Mordukhovich I, Coull B. Symptoms related to new flight attendant uniforms. BMC Public Health. 2018;17(1):972.

Michaelides MR, Kluge A, Patane M, Van Drie JH, Wang C, Hansen TM, Risi RM, Mantei R, Hertel C, Karukurichi K, Nesterov A, McElligott D, de Vries P, Langston JW, Cole PA, Marmorstein R, Liu H, Lasko L, Bromberg KD, Lai A, Kesicki EA. Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases. ACS Med Chem Lett. 2018;9(1):28-33.

Milman Krentsis I, Rosen C, Shezen E, Aronovich A, Nathanson B, Bachar-Lustig E, Berkman N, Assayag M, Shakhar G, Feferman T, Orgad R, Reisner Y. Lung Injury Repair by Transplantation of Adult Lung Cells Following Preconditioning of Recipient Mice. Stem Cells Transl Med. 2018;7(1):68-77.

Mor N, Rais Y, Sheban D, Peles S, Aguilera-Castrejon A, Zviran A, Elinger D, Viukov S, Geula S, Krupalnik V, Zerbib M, Chomsky E, Lasman L, Shani T, Bayerl J, Gafni O, Hanna S, Buenrostro JD, Hagai T, Masika H, Vainorius G, Bergman Y, Greenleaf WJ, Esteban MA, Elling U, Levin Y, Massarwa R, Merbl Y, Novershtern N, Hanna JH. Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency. Cell Stem Cell. 2018;23(3):412-425 e410.

Mulligan JK, Patel K, Williamson T, Reaves N, Carroll W, Stephenson SE, Gao P, Drake RR, Neely BA, Tomlinson S, Schlosser RJ, Atkinson C. C3a receptor antagonism as a novel therapeutic target for chronic rhinosinusitis. Mucosal Immunol. 2018;11(5):1375-1385.

Myers V, Shiloh S, Rosen L. Parental perceptions of children’s exposure to tobacco smoke: development and validation of a new measure. BMC Public Health. 2018;18(1):1031.

Nagaraja MR, Tiwari N, Shetty SK, Marudamuthu AS, Fan L, Ostrom RS, Fu J, Gopu V, Radhakrishnan V, Idell S, Shetty S. p53 Expression in Lung Fibroblasts Is Linked to Mitigation of Fibrotic Lung Remodeling. Am J Pathol. 2018;188(10):2207-2222.

Natarajan P, Peloso GM, Zekavat SM, Montasser M, Ganna A, Chaffin M, Khera AV, Zhou W, Bloom JM, Engreitz JM, Ernst J, O’Connell JR, Ruotsalainen SE, Alver M, Manichaikul A, Johnson WC, Perry JA, Poterba T, Seed C, Surakka IL, Esko T, Ripatti S, Salomaa V, Correa A, Vasan RS, Kellis M, Neale BM, Lander ES, Abecasis G, Mitchell B, Rich SS, Wilson JG, Cupples LA, Rotter JI, Willer CJ, Kathiresan S, Group NTLW. Deep-coverage whole genome sequences and blood lipids among 16,324 individuals. Nat Commun. 2018;9(1):3391.

Nath S, Ohlmeyer M, Salathe MA, Poon J, Baumlin N, Foronjy RF, Geraghty P. Chronic Cigarette Smoke Exposure Subdues PP2A Activity by Enhancing Expression of the Oncogene CIP2A. Am J Respir Cell Mol Biol. 2018;59(6):695-705.

Neophytou AM, Oh SS, White MJ, Mak ACY, Hu D, Huntsman S, Eng C, Serebrisky D, Borrell LN, Farber HJ, Meade K, Davis A, Avila PC, Thyne SM, Rodriguez-Cintron W, Rodriguez-Santana JR, Kumar R, Brigino-Buenaventura E, Sen S, Lenoir MA, Williams LK, Benowitz NL, Balmes JR, Eisen EA, Burchard EG. Secondhand smoke exposure and asthma outcomes among African-American and Latino children with asthma. Thorax. 2018;73(11):1041-1048.

Ooki A, Dinalankara W, Marchionni L, Tsay JJ, Goparaju C, Maleki Z, Rom WN, Pass HI, Hoque MO. Epigenetically regulated PAX6 drives cancer cells toward a stem-like state via GLI-SOX2 signaling axis in lung adenocarcinoma. Oncogene. 2018;37(45):5967-5981.

Ooki A, VandenBussche CJ, Kates M, Hahn NM, Matoso A, McConkey DJ, Bivalacqua TJ, Hoque MO. CD24 regulates cancer stem cell (CSC)-like traits and a panel of CSC-related molecules serves as a non-invasive urinary biomarker for the detection of bladder cancer. Br J Cancer. 2018;119(8):961-970.

Pabon MA, Patino E, Bhatia D, Rojas-Quintero J, Ma KC, Finkelsztein EJ, Osorio JC, Malick F, Polverino F, Owen CA, Ryter SW, Choi AM, Cloonan SM, Choi ME. Beclin-1 regulates cigarette smoke-induced kidney injury in a murine model of chronic obstructive pulmonary disease. JCI Insight. 2018;3(18).

Payne P, Fiering S, Zava D, Gould TJ, Brown A, Hage P, Gaudet C, Crane-Godreau M. Digital Delivery of Meditative Movement Training Improved Health of Cigarette-Smoke-Exposed Subjects. Frontiers in Public Health. 2018;6:282.

Petersen H, Sood A, Polverino F, Owen CA, Pinto-Plata V, Celli BR, Tesfaigzi Y. The Course of Lung Function in Middle-aged Heavy Smokers: Incidence and Time to Early Onset of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018;198(11):1449-1451.

Polverino F, Celli BR, Owen CA. COPD as an endothelial disorder: endothelial injury linking lesions in the lungs and other organs? (2017 Grover Conference Series). Pulm Circ. 2018;8(1):2045894018758528.

Polverino F, Celli BR, Owen CA. Reply to Voelkel: Cigarette Smoke Is an Endothelial Cell Toxin. Am J Respir Crit Care Med. 2018;197(2):274-275.

Polverino F, de Torres JP, Santoriello C, Capuozzo A, Mauro I, Rojas-Quintero J, D’Agostino B, Pistolesi M, Celli B, Polverino M, Owen CA. Gas exchange and breathing pattern in women with postmenopausal bone fragility. Respir Med. 2018;137:141-146.

Polverino F, Rojas-Quintero J, Wang X, Petersen H, Zhang L, Gai X, Higham A, Zhang D, Gupta K, Rout A, Yambayev I, Pinto-Plata V, Sholl LM, Cunoosamy D, Celli BR, Goldring J, Singh D, Tesfaigzi Y, Wedzicha J, Olsson H, Owen CA. A Disintegrin and A Metalloproteinase Domain-8 (ADAM8): A Novel Protective Proteinase in COPD. Am J Respir Crit Care Med. 2018.

Pulsipher A, Davis BM, Smith KA, Ashby S, Qin X, Firpo M, Orlandi RR, Alt JA. Calgranulin C (S100A12) Is Differentially Expressed in Subtypes of Chronic Rhinosinusitis. Am J Rhinol Allergy. 2018;32(5):380-387.

Raju SV, Rowe SM. Not simply the lesser of two evils. Am J Physiol Lung Cell Mol Physiol. 2018;314(2):L236-L238.

Ramakrishnan VR, Frank DN. Microbiome in patients with upper airway disease: Moving from taxonomic findings to mechanisms and causality. J Allergy Clin Immunol. 2018;142(1):73-75.

Ramakrishnan VR, Holt J, Nelson LF, Ir D, Robertson CE, Frank DN. Determinants of the Nasal Microbiome: Pilot Study of Effects of Intranasal Medication Use. Allergy Rhinol (Providence). 2018;9:2152656718789519.

Ravi Kumar S, Paudel S, Ghimire L, Bergeron S, Cai S, Zemans RL, Downey GP, Jeyaseelan S. Emerging Roles of Inflammasomes in Acute Pneumonia. Am J Respir Crit Care Med. 2018;197(2):160-171.

Rayavara K, Kurosky A, Stafford SJ, Garg NJ, Brasier AR, Garofalo RP, Hosakote YM. Proinflammatory Effects of Respiratory Syncytial Virus-Induced Epithelial HMGB1 on Human Innate Immune Cell Activation. J Immunol. 2018;201(9):2753-2766.

Rebuli ME, Pawlak EA, Walsh D, Martin EM, Jaspers I. Distinguishing Human Peripheral Blood NK Cells from CD56(dim)CD16(dim)CD69(+)CD103(+) Resident Nasal Mucosal Lavage Fluid Cells. Sci Rep. 2018;8(1):3394.

Reddy AT, Lakshmi SP, Banno A, Reddy RC. Identification and Molecular Characterization of Peroxisome Proliferator-Activated Receptor delta as a Novel Target for Covalent Modification by 15-Deoxy-Delta(12,14)-prostaglandin J2. ACS Chem Biol. 2018;13(12):3269-3278.

Reddy AT, Lakshmi SP, Banno A, Reddy RC. Role of GPx3 in PPARgamma-induced protection against COPD-associated oxidative stress. Free Radic Biol Med. 2018;126:350-357.

Reed RM, Cabral HJ, Dransfield MT, Eberlein M, Merlo CA, Mulligan MJ, Netzer G, Sanchez PG, Scharf SM, Sin DD, Celli BR. Survival of Lung Transplant Candidates With COPD: BODE Score Reconsidered. Chest. 2018;153(3):697-701.

Reeves AP, Xie Y, Liu S. Automated image quality assessment for chest CT scans. Med Phys. 2018;45(2):561-578.

Rosen L, Guttman N, Myers V, Brown N, Ram A, Hovell M, Breysse P, Rule A, Berkovitch M, Zucker D. Protecting Young Children From Tobacco Smoke Exposure: A Pilot Study of Project Zero Exposure. Pediatrics. 2018;141(Suppl 1):S107-S117.

Rosen LJ, Lev E, Guttman N, Tillinger E, Rosenblat S, Zucker DM, Myers V. Parental Perceptions and Misconceptions of Child Tobacco Smoke Exposure. Nicotine Tob Res. 2018;20(11):1369-1377.

Rydzak CE, Armato SG, Avila RS, Mulshine JL, Yankelevitz DF, Gierada DS. Quality assurance and quantitative imaging biomarkers in low-dose CT lung cancer screening. Br J Radiol. 2018;91(1090):20170401.

Saini Y, Lewis BW, Yu D, Dang H, Livraghi-Butrico A, Del Piero F, O’Neal WK, Boucher RC. Effect of LysM+ macrophage depletion on lung pathology in mice with chronic bronchitis. Physiol Rep. 2018;6(8):e13677.

Salvatore M, Margolies L, Bertolini A, Singh A, Yankelevitz D, Henschke C. The need to be all inclusive: Chest CT scans should include imaged breast parenchyma. Clin Imaging. 2018;50:243-245.

Sauler M, Lamontagne M, Finnemore E, Herazo-Maya JD, Tedrow J, Zhang X, Morneau JE, Sciurba F, Timens W, Pare PD, Lee PJ, Kaminski N, Bosse Y, Gomez JL. The DNA repair transcriptome in severe COPD. Eur Respir J. 2018;52(4).

Shabbir A, Esfandyari T, Farassati F. Cancer stem cells, the ultimate targets in cancer therapy. Onco Targets Ther. 2018;11:183-184.

Shanholtz C, Reed RM, Brower RG. ECMO for Severe Acute Respiratory Distress Syndrome. N Engl J Med. 2018;379(11):1090.

Singh A, Ruiz C, Bhalla K, Haley JA, Li QK, Acquaah-Mensah G, Montal E, Sudini KR, Skoulidis F, Wistuba, II, Papadimitrakopoulou V, Heymach JV, Boros LG, Gabrielson E, Carretero J, Wong KK, Haley JD, Biswal S, Girnun GD. De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer. FASEB J. 2018:fj201800204.

Singh DP, Kaur G, Bagam P, Pinkston R, Batra S. Membrane microdomains regulate NLRP10- and NLRP12-dependent signalling in A549 cells challenged with cigarette smoke extract. Arch Toxicol. 2018;92(5):1767-1783.

Smith KA, Pulsipher A, Gabrielsen DA, Alt JA. Biologics in Chronic Rhinosinusitis: An Update and Thoughts for Future Directions. Am J Rhinol Allergy. 2018;32(5):412-423.

So JY, Zhao H, Voelker H, Reed RM, Sin D, Marchetti N, Criner GJ. Seasonal and Regional Variations in Chronic Obstructive Pulmonary Disease Exacerbation Rates in Adults without Cardiovascular Risk Factors. Ann Am Thorac Soc. 2018;15(11):1296-1303.

Solanki HS, Raja R, Zhavoronkov A, Ozerov IV, Artemov AV, Advani J, Radhakrishnan A, Babu N, Puttamallesh VN, Syed N, Nanjappa V, Subbannayya T, Sahasrabuddhe NA, Patil AH, Prasad TSK, Gaykalova D, Chang X, Sathyendran R, Mathur PP, Rangarajan A, Sidransky D, Pandey A, Izumchenko E, Gowda H, Chatterjee A. Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor. Oncoscience. 2018;5(1-2):21-38.

Solomon H, Dinowitz N, Pateras IS, Cooks T, Shetzer Y, Molchadsky A, Charni M, Rabani S, Koifman G, Tarcic O, Porat Z, Kogan-Sakin I, Goldfinger N, Oren M, Harris CC, Gorgoulis VG, Rotter V. Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers. Oncogene. 2018;37(12):1669-1684.

Sottile PD, Kiser TH, Burnham EL, Ho PM, Allen RR, Vandivier RW, Moss M, Colorado Pulmonary Outcomes Research G. An Observational Study of the Efficacy of Cisatracurium Compared with Vecuronium in Patients with or at Risk for Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2018;197(7):897-904.

Strauss KA, Carson VJ, Brigatti KW, Young M, Robinson DL, Hendrickson C, Fox MD, Reed RM, Puffenberger EG, Mackenzie W, Miller F. Preliminary Safety and Tolerability of a Novel Subcutaneous Intrathecal Catheter System for Repeated Outpatient Dosing of Nusinersen to Children and Adults With Spinal Muscular Atrophy. J Pediatr Orthop. 2018;38(10):e610-e617.

Sulaiman I, Wu BG, Li Y, Scott AS, Malecha P, Scaglione B, Wang J, Basavaraj A, Chung S, Bantis K, Carpenito J, Clemente JC, Shen N, Bessich J, Rafeq S, Michaud G, Donington J, Naidoo C, Theron G, Schattner G, Garofano S, Condos R, Kamelhar D, Addrizzo-Harris D, Segal LN. Evaluation of the airway microbiome in nontuberculous mycobacteria disease. Eur Respir J. 2018;52(4).

Talbot M, Hamel-Auger M, Beaulieu MJ, Gazzola M, Lechasseur A, Aubin S, Pare ME, Marsolais D, Bosse Y, Morissette MC. Impact of immunization against OxLDL on the pulmonary response to cigarette smoke exposure in mice. Respir Res. 2018;19(1):131.

Tan LH, Bahmed K, Lin CR, Marchetti N, Bolla S, Criner GJ, Kelsen S, Madesh M, Kosmider B. The cytoprotective role of DJ-1 and p45 NFE2 against human primary alveolar type II cell injury and emphysema. Sci Rep. 2018;8(1):3555.

Tartaglione G, Spaziano G, Sgambato M, Russo TP, Liparulo A, Esposito R, Mirra S, Filosa R, Roviezzo F, Polverino F, D’Agostino B. Nociceptin/Orphanin Fq in inflammation and remodeling of the small airways in experimental model of airway hyperresponsiveness. Physiol Rep. 2018;6(20):e13906.

Terai K, Bi D, Liu Z, Kimura K, Sanaat Z, Dolatkhah R, Soleimani M, Jones C, Bright A, Esfandyari T, Farassati F. A Novel Oncolytic Herpes Capable of Cell-Specific Transcriptional Targeting of CD133+/- Cancer Cells Induces Significant Tumor Regression. Stem Cells. 2018;36(8):1154-1169.

Trinity JD, Layec G, Hart CR, Richardson RS. Sex-specific impact of aging on the blood pressure response to exercise. Am J Physiol Heart Circ Physiol. 2018;314(1):H95-H104.

Turino GM, Ma S, Lin YY, Cantor JO. The Therapeutic Potential of Hyaluronan in COPD. Chest. 2018;153(4):792-798.

Turino GM. Chronic Obstructive Pulmonary Disease. A Biomarker and a Potential Therapy. Ann Am Thorac Soc. 2018;15(Supplement_1):S15-S17.

Uang R, Crosbie E, Glantz SA. Tobacco control law implementation in a middle-income country: Transnational tobacco control network overcoming tobacco industry opposition in Colombia. Glob Public Health. 2018;13(8):1050-1064.

Uche IK, Guerrero-Plata A. Interferon-Mediated Response to Human Metapneumovirus Infection. Viruses. 2018;10(9).

Veronesi G, Zulueta JJ, Maisonneuve P, Henschke C. At last we can go ahead with low-dose CT screening for lung cancer in Europe. Lung Cancer. 2018;123:176-177.

Vij N, Chandramani-Shivalingappa P, Van Westphal C, Hole R, Bodas M. Cigarette smoke-induced autophagy impairment accelerates lung aging, COPD-emphysema exacerbations and pathogenesis. Am J Physiol Cell Physiol. 2018;314(1):C73-C87.

Wang C, de Mochel NSR, Christenson SA, Cassandras M, Moon R, Brumwell AN, Byrnes LE, Li A, Yokosaki Y, Shan P, Sneddon JB, Jablons D, Lee PJ, Matthay MA, Chapman HA, Peng T. Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype. J Clin Invest. 2018;128(10):4343-4358.

Wang X, Polverino F, Rojas-Quintero J, Zhang D, Sanchez J, Yambayev I, Lindqvist E, Virtala R, Djukanovic R, Davies DE, Wilson S, O’Donnell R, Cunoosamy D, Hazon P, Higham A, Singh D, Olsson H, Owen CA. A Disintegrin and A Metalloproteinase-9 (ADAM9): A Novel Proteinase Culprit with Multifarious Contributions to COPD. Am J Respir Crit Care Med. 2018.

Wei Y, Chhiba KD, Zhang F, Ye X, Wang L, Zhang L, Robida PA, Moreno-Vinasco L, Schnaar RL, Roers A, Hartmann K, Lee CM, Demers D, Zheng T, Bochner BS, Zhu Z. Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice. Int J Mol Sci. 2018;20(1).

Weinert BT, Narita T, Satpathy S, Srinivasan B, Hansen BK, Scholz C, Hamilton WB, Zucconi BE, Wang WW, Liu WR, Brickman JM, Kesicki EA, Lai A, Bromberg KD, Cole PA, Choudhary C. Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome. Cell. 2018;174(1):231-244 e212.

Wilson KM, Torok MR, Wei B, Wang L, Lowary M, Blount BC. Marijuana and Tobacco Coexposure in Hospitalized Children. Pediatrics. 2018;142(6).

Wu BG, Segal LN. The Lung Microbiome and Its Role in Pneumonia. Clin Chest Med. 2018;39(4):677-689.

Wu BG, Segal LN. The Road to Precision Medicine in Chronic Obstructive Pulmonary Disease: Squeezing More Out of Chest Computed Tomography Scans. Ann Am Thorac Soc. 2018;15(4):428-429.

Wu BG, Sulaiman I, Wang J, Shen N, Clemente JC, Li Y, Laumbach RJ, Lu SE, Udasin I, Le-Hoang O, Perez A, Alimokhtari S, Black K, Plietz M, Twumasi A, Sanders H, Malecha P, Kapoor B, Scaglione BD, Wang A, Blazoski C, Weiden MD, Rapoport DM, Harrison D, Chitkara N, Vicente E, Marin JM, Sunderram J, Ayappa I, Segal LN. Severe Obstructive Sleep Apnea is Associated with Alterations in the Nasal Microbiome and Increase in Inflammation. Am J Respir Crit Care Med. 2018.

Wu M, Hayward D, Kalin JH, Song Y, Schwabe JW, Cole PA. Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex. Elife. 2018;7.

Wu Q, Jiang D, Schaefer NR, Harmacek L, O’Connor BP, Eling TE, Eickelberg O, Chu HW. Overproduction of growth differentiation factor 15 promotes human rhinovirus infection and virus-induced inflammation in the lung. Am J Physiol Lung Cell Mol Physiol. 2018;314(3):L514-L527.

Yankelevitz DF. CT Screening for Lung Cancer: Successful Trial, but Failed Understanding. J Thorac Oncol. 2018;13(1):12-15.

Yankelevitz DF. Invited Commentary: Early Lung Cancer and Cystic Airspaces. Radiographics. 2018;38(3):717-718.

Yip R, Li K, Liu L, Xu D, Tam K, Yankelevitz DF, Taioli E, Becker B, Henschke CI. Controversies on lung cancers manifesting as part-solid nodules. Eur Radiol. 2018;28(2):747-759.

Yu G, Tzouvelekis A, Wang R, Herazo-Maya JD, Ibarra GH, Srivastava A, de Castro JPW, DeIuliis G, Ahangari F, Woolard T, Aurelien N, Arrojo EDR, Gan Y, Graham M, Liu X, Homer RJ, Scanlan TS, Mannam P, Lee PJ, Herzog EL, Bianco AC, Kaminski N. Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function. Nat Med. 2018;24(1):39-49.

Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J, Chaffin M, Engreitz J, Peloso GM, Manichaikul A, Yang C, Ryan KA, Fu M, Johnson WC, Tsai M, Budoff M, Vasan RS, Cupples LA, Rotter JI, Rich SS, Post W, Mitchell BD, Correa A, Metspalu A, Wilson JG, Salomaa V, Kellis M, Daly MJ, Neale BM, McCarroll S, Surakka I, Esko T, Ganna A, Ripatti S, Kathiresan S, Natarajan P, Group NTLW. Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. Nat Commun. 2018;9(1):2606.

Presentations and Abstracts 2018

Arjomandi M, Zeng S, Blanc PD, Gold WM. Increasing the resolution of chronic obstructive pulmonary disease definition. lessons from a cohort with remote but extensive exposure to secondhand tobacco smoke. Ann Am Thorac Soc 2018;15(Supplement_2):S122-S123.

Barnes J, Duncan DE, Kurundkar D, Hutcheson S, Logsdon NJ, Locy M, Blumhof S, Helton S, King G, Thannickal V, Krick S. Role of the anti-aging hormone klotho in idiopathic pulmonary fibrosis. Presented at the ATS International Conference. San Diego, CA, May 19-23, 2018.

Barrero CA, Fecchio C, Rizzatello G, Olusajo VO, Rico MC, Perez-Leal O, Criner GJ, Merali S. Histone 3.3 as a biomarker for COPD exacerbation [abstract]. Am J Respir Crit Care Med 2018;197:A779.

Barrero CA, Rico MC, Kosmider B, Perez-Lea OM, Fecchio C, Olusajo V, Vij N, Thanavala Y, Bahmed K, Barbe MF, Criner GK.  Extracellular histone H3.3 damages lung tissue and induce a systemic inflammatory response [abstract].  Am J Respir Crit Care Med 2018;197:A7683.

Barrero CA. Identifying novel disease modifying drugs for the treatment of chronic obstructive pulmonary diseases, ATS 2018 BEAR Cage Finalist presentation. San Diego, CA, May 21, 2018.

Blumhof  S, Hutcheson S, Eason-Duncan D, Russell D, Viera L, Wells JM, King G, Krick S, Barnes JW.  Inflammatory and oxidative stress in the airway epithelium are mediated through O-Linked N-acetyl-glucosamine modification and regulated by FGF23 [abstract].  Am J Respir Crit Care Med 2018;197:A6357.

Blumhof  S, Hutcheson S, Duncan D, Russell D, Viera  L, Wells JM, King G, Barnes JW, Krick S.  FGF23 regulates inflammation and oxidative stress through O-linked N-acetyl-glucosamine modification in the airway epithelium. Presented at the Southern Society for Clinical Investigation meeting, Feb 23, 2018.

Che P, Yu L, Zhao X-K, Wang  M, Gaggar  A, Blalock JE, Ding Q.  Cigarette smoke decreases tristetraprolin expression through p38-mediated pathway. Presented at the ATS International Conference. San Diego, CA, May 19-23, 2018.

Cheemarla NR, Guerrero-Plata A.  Prenatal smoke exposure exacerbates lung inflammatory response by increasing neutrophils infiltration to the lungs after RSV infection. Presented at the American Association of Immunologists. Austin, TX, May 4-8, 2018.

Cheemarla NR, Guerrero-Plata A.  Prenatal smoke exposure exacerbates lung inflammatory response by modulating neutrophil infiltration to the lungs after RSV infection. Presented at the PhiZeta Research Emphasis Day. Baton Rouge, LA, Feb 28, 2018.

Cummings, KM. A Century of Cigarettes. Presented at the Montana Public Health Association Annual Meeting. Helena, MT, Sep 2018.

Cummings, KM. A Century of Cigarettes. Presented at the Say What! Texas Tobacco-Free Conference. San Marcos, TX, July 2018.

Cummings, KM. The Evolving Cigarette. Presented at the American Society for Preventive Cardiology’s 2018 Congress on CVD Prevention. Santa Ana Pueblo, NM, Jul 2018.

Cummings, KM. The Evolving Cigarette. Presented at the IASLC 19th world conference on lung cancer. Toronto, Canada, Sep 2018.

Cummings, KM. The Evolving Cigarette. Presented at the Roswell Park Cancer Inst. Tobacco Treatment Specialist Training Program. Sep 2018.

Cummings, KM. The Evolving Cigarette. Presented at the SRNT 24th Annual Meeting. Baltimore, MD, Feb 2018.

Diaz del Valle F, Zakrajsek J, Bell HW, Ramakrishnan VR, Frank DN, Vandivier RW. Long-term impact of remote environmental tobacco smoke exposure on respiratory symptoms and quality of life. Presented at the Thomas L. Petty Lung Conference. Aspen, CO, Jun 6-9, 2018.

Fan L, Gopu V, Tiwari N, Marudamuthu AS, Shetty SK, Bhandary YP, Nagaraja MR, Radhakrishnan V, MacKenzie B, Watts AB, Maier E, Williams RO, Idell S, Shetty S.  Resolution of pulmonary fibrosis by a caveolin-1-derived peptide [abstract]. Am J Respir Crit Care Med 2018;197:A2221.

Gopu V, Shetty SK, Mavanoor N, Bhandary Y, Idell S, Shetty S.  Caveolin scaffolding peptide regulates glucose metabolism in lung fibrosis [abstract].  Am J Respir Crit Care Med 2018;197:A3875.

Gorzkowski J, Brishke J, Marbin J, Boykan R, Walley S, Groner J, Kraft C, Winickoff J, Tanski S, Tait V. Asking the right questions: training pediatricians to address tobacco cessation in the clinical encounter. Presented at the Society for Research on Nicotine and Tobacco meeting. Baltimore, MD, Feb 21-24, 2018.

Gulati S, Urdaneta GP, Balestrini K, Vital I, Campos M, Krick S.  Fibroblast growth factor 23 is associated with chronic obstructive pulmonary disease exacerbations: a pilot study [abstract]. Am J Respir Crit Care Med 2018;197:A4755.

Hirschi KM, Egbert K, Clark C, Mella N, Plothow E, Mejia JF, Arroyo JA, Reynolds PR. Antenatal exposure to secondhand smoke impacts growth and cardiopulmonary energetics in 4-week old mice. Presented at the Experimental Biology. Conference. San Diego, CA, Apr 21-25, 2018.

Hosakote YM, Rayavara K, Hallberg LM, Ameredes BT, Kurosky A. Antioxidant treatment ameliorates cigarette smoke and respiratory syncytial virus-induced inflammatory response by blocking HMGB1 release. J Immunol 2018;200(1 Supplement)166.6.

Jacobsen C, Dalanhese D, Peterson M, Sarva S, Chapman S, Mejia J, Bikman B,  Reynolds P, Arroyo J.  Reduction of CSE-induced Ca9-22 Cell Invasion by SAGEs.  Presented at the AADR Annual Meeting. Fort Lauderdale, FL, Mar 21-24, 2018.

Kovacs L, Cao Y, Han W, Meadows L, Kovacs-Kasa A, Verin A, Barman S, Huo Y, Su Y.  Increased glycolysis contributes to pulmonary vascular remodeling via ERK-dependent calpain activation in pulmonary arterial hypertension. FASEB J 2018;32,:(1)Supplement.

McGrath-Morrow, S. Health effects of e-cigarettes. Symposium presentation at the 2018 Society for Research on Nicotine and Tobacco Meeting. Baltimore, MD, Feb 21-24, 2018.

McMillen R, Gorzkowski J, Wilson K, Klein J, Winickoff J. Smokefree homes are associated with better health and fewer ER visits, Presented at the PAS Annual Meeting,.Toronto, Canada, May 5-8, 2018.

McMillen R, Klein JD, Wilson K, Winickoff JP, Tanski S. E-Cigarette use is associated with future cigarette initiation among never-smokers and relapse among distant former smokers: results from two waves of the PATH study. Presented at the 2018 Society for Research on Nicotine and Tobacco conference. Baltimore, MD, Feb 21-24, 2018.

McMillen R, Wilson K, Gorzkowski J, Winickoff J, Klein J. E-Cigarette use and motivation for use predicts future cigarette smoking among youth. Presented at the PAS Annual Meeting,.Toronto, Canada, May 5-8, 2018.

Myers V,, Shiloh S, Rosen LJ. Low parental perceptions of exposure are associated with riskier parental smoking behaviour. Presented at the Annual Conference of Public Health Physicians and Schools of Public Health. Ramat Gan, Israel, Jun 2018.

Myers-Gamliel V, Lev E, Guttman N, Tillinger E, Rosen L. How parents attempt to protect their children from harm from smoking: Practical approaches (not always effective), dilemmas and conflicts. Presented at the 8th Conference on Qualitative Research, Israel Center for Qualitative Research of People and Societies. Ben Gurion University, Beersheba Israel, Jan 2018.

Myers-Gamliel V, Shilo S, Rosen L. Parental perceptions of exposure – a new tool to examine parental understanding of children’s exposure to tobacco smoke. Presented at the World Conference on Tobacco or Health. CapeTown, South Africa, Mar 2018.

Numata-Nakamura M, Bochkov YA, Seibold MA, Everman J, Lee H, Voelker DR. Pulmonary surfactant lipids antagonize human rhinovirus infection [abstract].  Am J Resp Crit Care Med 2018;197:A3850.

Olusajo V, Wang F, Rico M, Criner G, Barrero CA. Cigarette smoke exposure induces acetylated histone 3.3 (AcH3.3) accumulation.  Presented at the American Society of Health-System Pharmacists (ASHP), Midyear Clinical Meeting. Anaheim, CA, Dec 2018.

Ostergar A, Egbert K, Clark C, Hall P, Davis T, Hirschi KM, Arroyo JA, Reynolds PR. Semi-Synthetic Glycosaminoglycan ethers decrease Receptors for Advanced Glycation End-Products and increase AXL receptor in the lung from secondhand smoke treated mice. Experimental Biology. San Diego, CA, Apr 21-25, 2018.

Peterson M, Sarva S, Jacobsen C, Dalanhese D, Hirschi K, Chapman S, Hall P, Bikman B, Reynolds PR, Arroyo J.  Decreased inflammatory cytokines during Gas6-mediated invasion of gingival cells. Presented at the American Association for Dental Research Meeting. Ft. Lauderdale, FL, Mar 21-24, 2018.

Price K, Kimbler B, Knowlton N, Franson L, Hirschi KM, Reynolds PR, Arroyo JA.  Differential expression of mTOR related molecules in the placenta of gestational diabetes mellitus (GDM), intrauterine growth restriction (IUGR) and preeclampsia patients. Presented at the Experimental Biology International Meeting. San Diego, CA, Apr 21-25, 2018.

Pulsipher A, Alt JA. A novel, glycosaminoglycan-based therapeutic for chronic rhinosinusitis. Presented at the Respiratory Innovation Summit. San Diego, CA, May 19, 2018.

Rayavara K, Kurosky A, Hosakote YM. Effects of HMGB1 gene silencing on respiratory syncytial virus-induced inflammatory response. J Immunol 2018;200(1 Supplement)166.7.

Soler ZM. The impact of medical therapy on cognitive dysfunction in chronic rhinosinusitis. Presented at the 64th Annual Meeting of the American Rhinologic Society. Atlanta, GA, Oct 6, 2018.

Talitman M, Steinberg D, Kalkbrenner AE, Hovell M, Rosen LJ. Association between biomarkers and parentally-reported measures of child tobacco smoke exposure: A secondary analysis of data from three trials. Presented at the Annual Conference of Public Health Physicians and Schools of Public Health. Ramat Gan, Israel, Jun 2018.

Tiwari N, Nagaraja MR, Shetty SK, Marudamuthu AS, Fan L, Ostrom RS, Fu J, Gopu V, Idell S, Shetty S. p53 Expression in lung fibroblasts: Linkage to fibrotic lung remodeling [abstract]. Am J Respir Crit Care Med 2018;197:A5789.

Wu BG, Wang J, Sulaiman I, Shen N, Clemente J, Li Y, Laumbach RJ, Lu S, Udasin I, Le-Hoang O, Perez A, Horowitz A, Alimokhtari S, Black K, Plietz M, Twumasi A, Melacha P, Kapoor B, Scaglione BD, Blazoski CM, Wang A, Gilani J, Vicente EA, Marin JM, Weiden M, Rapoport DM, Sunderram J, Ayappa IA, Segal LN. Severe obstructive sleep apnea is associated with changes in nasal microbiota. Presented at ATS International Conference. San Diego, CA, May 21, 2018.

Wu BG, Xiao R, Perez L, Franca B, Wang A, Carpenito J, Blazoski C, Olsen E, Zelonina T, Li Y, Blaser MJ, D’Armiento JM, Segal LN. Smoke-associated microbiome exposure leads to alteration of inflammation that impacts emphysema development. Presented at the ATS International Conference. San Diego, CA, May 23, 2018.

Wu Q, Jiang D, Schaefer N, Harmacek L, O’Connor BP, Eling TE, Eickelberg O, Chu H.  Over-production of growth differentiation factor 15 (GDF15) promotes human rhinovirus infection and virus-induced inflammation in the lung [abstract]. ATS International Conference. San Diego, CA, May 18-23, 2018.

Wu Q, Ren WH, Ye SY, Koenigshoff M, Eickelberg O. Growth differentiation factor 15 (GDF15)-mediated lung aging promotes respiratory human rhinovirus infection. Presented at the Thomas l. Petty Aspen Lung Conference 61st Annual Meeting. Aspen, CO, Jun 6-9, 2018.

Wu W, Choi EJ, Ren Y, Chen Y, Liu S, Ren J, Garofalo RP, Zhou J, Bao X. Exchange proteins directly activated by cAMP and the role of these proteins in respiratory syncytial virus infection [abstract].  AAI Meeting, Austin, TX, May 4-8, 2018, J Immunol 2018;200 (1): Supplement).

Zakrajsek JK, Bell HW, Diaz del Valle F, Frank DN, Zamora MR, Lee JS, Phang TL, Ginde AA, Kiser TH, Abrams ME, Tallieu SS, Gerber AN and Vandivier RW.  Recovery following COPD exacerbations associated with respiratory failure. Presented at the Thomas L. Petty Lung Conference. Aspen, CO, Jun 6-9, 2018.

Zeng S, Tham A, Bos B, Jin J, Arjomandi M. Back to the Box: Using Lung Volumes to Predict Susceptibility to Develop Chronic Obstructive Pulmonary Disease among Smokers. Ann Am Thorac Soc. 2018;15(Supplement_4):S286-S287.

Zhu J, Han W, Su Y. Inhibition of calpain attenuates airway and pulmonary vascular remodeling in COPD [abstract]. Am J Respir Crit Care Med 2018;197:A7132.

Book Chapters, etc., 2018

Liu, J, Sun Z, Peiffer BJ, Wang Y, Ahmadi AR, Guo Z, Peng H, Ahmad A. Invention disclosure: “Non-immunosuppressive FK506 analogs and use thereof”. 2018.

McGrath-Morrow SA: Committee member. Public Health Consequences of E-Cigarettes. National Academies of Sciences, Engineering, and Medicine. Washington, DC: The National Academies Press. https://doi.org/10.17226/24952, 2018.

 

References

References
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