Publications 2020

Agudelo CW, Kumley BK, Area-Gomez E, Xu Y, Dabo AJ, Geraghty P, Campos M,
Foronjy R, Garcia-Arcos I. Decreased surfactant lipids correlate with lung function in chronic obstructive pulmonary disease (COPD). PLoS One. 2020;15(2):e0228279.

Agudelo CW, Samaha G, Garcia-Arcos I. Alveolar lipids in pulmonary disease. A
review. Lipids Health Dis. 2020;19(1):122.
Aloni-Grinstein R, Stine Y, Rotter V. Influenza A virus and p53: Can the two walk together? A Commentary on “p53 and the viral connection: back into the future” [commentary]. J Lung Heal Dis. 2020;4:1-4.

Barrett TJ, Wu BG, Revenko AS, MacLeod AR, Segal LN, Berger JS. Antisense
oligonucleotide targeting of thrombopoietin represents a novel platelet depletion method to assess the immunomodulatory role of platelets. J Thromb Haemost. 2020;18(7):1773-1782.

Berg OK, Kwon OS, Hureau TJ, Clifton HL, Thurston TS, Le Fur Y, Jeong EK, Trinity JD,
Richardson RS, Wang E, Layec G. Skeletal Muscle Mitochondrial Adaptations to
Maximal Strength Training in Older Adults. J Gerontol A Biol Sci Med Sci.
2020;75(12):2269-2277.

Blagev DP, Collingridge DS, Rea S, Carey KA, Mularski RA, Zeng S, Arjomandi M,
Press VG. Laboratory-based Intermountain Validated Exacerbation (LIVE) Score stability in patients with chronic obstructive pulmonary disease. BMJ Open Respir Res. 2020;7(1).

Boruk M, Dabo AJ, Nath S, Zahid K, Ploszaj M, Wu D, Rosenfeld R, Foronjy RF, Geraghty P. Elevated levels of calpain 14 in nasal tissue in chronic rhinosinusitis. ERJ Open Res. 2020;6(3).

Boruk M, Railwah C, Lora A, Nath S, Wu D, Chow L, Borhanjoo P, Dabo AJ, Chowdhury S, Kaiser R, Foronjy RF, Rosenfeld R, Geraghty P. Elevated S100A9 expression in chronic rhinosinusitis coincides with elevated MMP production and proliferation in vitro. Sci Rep. 2020;10(1):16350.

Brown R, Nath S, Lora A, Samaha G, Elgamal Z, Kaiser R, Taggart C, Weldon S, Geraghty P. Cathepsin S: investigating an old player in lung disease pathogenesis, comorbidities, and potential therapeutics. Respir Res. 2020;21(1):111.

Brozman O, Novak J, Bauer AK, Babica P. Airborne PAHs inhibit gap junctional
intercellular communication and activate MAPKs in human bronchial epithelial cell
line. Environ Toxicol Pharmacol. 2020;79:103422.

Che P, Wagener BM, Zhao X, Brandon AP, Evans CA, Cai GQ, Zhao R, Xu ZX, Han X, Pittet JF, Ding Q. Neuronal Wiskott-Aldrich syndrome protein regulates Pseudomonas aeruginosa-induced lung vascular permeability through the modulation of actin cytoskeletal dynamics. FASEB J. 2020;34(2):3305-3317.

Chen X, Ma T, Yip R, Perumalswami PV, Branch AD, Lewis S, Crane M, Yankelevitz DF, Henschke CI. Elevated prevalence of moderate-to-severe hepatic steatosis in World Trade Center General Responder Cohort in a program of CT lung screening. Clin Imaging. 2020;60(2):237-243.

Chung S, Bengtson CD, Kim MD, Salathe M. CrossTalk opposing view: E-cigarettes
expose users to adverse effects of vapours and the potential for nicotine addiction. J
Physiol. 2020;598(15):3053-3056.

Chung S, Bengtson CD, Kim MD, Salathe M. Rebuttal from Samuel Chung, Charles D. Bengtson, Michael D. Kim and Matthias Salathe. J Physiol. 2020;598(15):3059-3060.

Clapham KR, Rao Y, Sahay S, Sauler M, Lee PJ, Psotka MA, Fares WH, Ahmad T.
PECAM-1 is Associated WithOutcomes and Response to Treatment in Pulmonary
Arterial Hypertension. Am J Cardiol. 2020;127:198-199.

Crane-Godreau MA, Clem KJ, Payne P, Fiering S. Vitamin D Deficiency and Air
Pollution Exacerbate COVID-19 Through Suppression of Antiviral Peptide LL37.
Front Public Health. 2020;8:232.

Dabo AJ, Ezegbunam W, Wyman AE, Moon J, Railwah C, Lora A, Majka SM, Geraghty P, Foronjy RF. Targeting c-Src Reverses Accelerated GPX-1 mRNA Decay in Chronic Obstructive Pulmonary Disease Airway Epithelial Cells. Am J Respir Cell Mol Biol. 2020;62(5):598-607.

Datan E, Minn I, Xu P, He QL, Ahn HH, Yu B, Pomper MG, Liu JO. A Glucose-Triptolide Conjugate Selectively Targets Cancer Cells under Hypoxia. iScience.
2020;23(9):101536.

Easter M, Bollenbecker S, Barnes JW, Krick S. Targeting Aging Pathways in Chronic Obstructive Pulmonary Disease. Int J Mol Sci. 2020;21(18).

Easter M, Garth J, Harris ES, Shei RJ, Helton ES, Wei Y, Denson R, Zaharias R, Rowe SM, Geraghty P, Faul C, Barnes JW, Krick S. Fibroblast Growth Factor Receptor 4 Deficiency Mediates Airway Inflammation in the Adult Healthy Lung? Front Med (Lausanne). 2020;7:317.

Foronjy R. Commentary on: The potency of lncRNA MALAT1/miR-155 in altering
asthmatic Th1/Th2 balance by modulation of CTLA4. Biosci Rep. 2020;40(5).

Gomez JL, Chen A, Diaz MP, Zirn N, Gupta A, Britto C, Sauler M, Yan X, Stewart E, Santerian K, Grant N, Liu Q, Fry R, Rager J, Cohn L, Alexis N, Chupp GL. A Network of Sputum MicroRNAs Is Associated with Neutrophilic Airway Inflammation in Asthma. Am J Respir Crit Care Med. 2020;202(1):51-64.

Gopu V, Fan L, Shetty RS, Nagaraja MR, Shetty S. Caveolin-1 scaffolding domain
peptide regulates glucose metabolism in lung fibrosis. JCI Insight. 2020;5(19).
Gupta G, Baumlin N, Poon J, Ahmed B, Chiang YP, Railwah C, Kim MD, Rivas M,
Goldenberg H, Elgamal Z, Salathe M, Panwala AA, Dabo A, Huan C, Foronjy R, Jiang XC, Wadgaonkar R, Geraghty P. Airway Resistance Caused by Sphingomyelin Synthase 2 Insufficiency in Response to Cigarette Smoke. Am J Respir Cell Mol Biol. 2020;62(3):342-353.

Hayashi M, Guida E, Inokawa Y, Goldberg R, Reis LO, Ooki A, Pilli M, Sadhukhan P, Woo J, Choi W, Izumchenko E, Gonzalez LM, Marchionni L, Zhavoronkov A, Brait M, Bivalacqua T, Baras A, Netto GJ, Koch W, Singh A, Hoque MO. GULP1 regulates the
NRF2-KEAP1 signaling axis in urothelial carcinoma. Sci Signal. 2020;13(645).

Hecht HS. Coronary Artery Calcium: From the Power of 0 to >1,000. JACC Cardiovasc Imaging. 2020;13(1 Pt 1):94-96.

Henkel M, Partyka J, Gregory AD, Forno E, Cho MH, Eddens T, Tout AR, Salamacha N, Horne W, Rao KS, Wu Y, Alcorn JF, Kostka D, Hirsch R, Celedon JC, Shapiro SD, Kolls JK, Campfield BT. FSTL-1 Attenuation Causes Spontaneous Smoke-Resistant Pulmonary Emphysema. Am J Respir Crit Care Med. 2020;201(8):934-945.

Hosseini M, Farassati FS, Farassati F. Targeting Cancer Stem Cells by Oncolytic
Viruses and Nano-Mediated Delivery. Onco Targets Ther. 2020;13:9349-9350.

Ives SJ, Layec G, Hart CR, Trinity JD, Gifford JR, Garten RS, Witman MAH, Sorensen JR, Richardson RS. Passive leg movement in chronic obstructive pulmonary disease: evidence of locomotor muscle vascular dysfunction. J Appl Physiol (1985). 2020;128(5):1402-1411.

Jenssen BP, Kelly MK, Faerber J, Hannan C, Asch DA, Shults J, Schnoll RA, Fiks AG. Parent Preferences for Pediatric Clinician Messaging to Promote Smoking Cessation Treatment. Pediatrics. 2020;146(1).

Jirapatnakul A, Reeves AP, Lewis S, Chen X, Ma T, Yip R, Chin X, Liu S, Perumalswami PV, Yankelevitz DF, Crane M, Branch AD, Henschke CI. Automated measurement of liver attenuation to identify moderate-to-severe hepatic steatosis from chest CT scans. Eur J Radiol. 2020;122:108723.

Kapoor A, Ghosh AK, Forman M, Hu X, Ye W, Southall N, Marugan J, Keyes RF, Smith BC, Meyers DJ, Ferrer M, Arav-Boger R. Validation and Characterization of Five Distinct Novel Inhibitors of Human Cytomegalovirus. J Med Chem. 2020;63(8):3896-
3907.

Kaur G, Batra S. Regulation of DNA methylation signatures on NF-kappaB and STAT3 pathway genes and TET activity in cigarette smoke extract-challenged cells/COPD exacerbation model in vitro. Cell Biol Toxicol. 2020.

Khurana N, Pulsipher A, Jedrzkiewicz J, Ashby S, Pollard CE, Ghandehari H, Alt JA. Inflammation-driven vascular dysregulation in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2020.

Kim BS, Tilstam PV, Arnke K, Leng L, Ruhl T, Piecychna M, Schulte W, Sauler M, Frueh FS, Storti G, Lindenblatt N, Giovanoli P, Pallua N, Bernhagen J, Bucala R. Differential regulation of macrophage activation by the MIF cytokine superfamily members MIF and MIF-2 in adipose tissue during endotoxemia. FASEB J. 2020;34(3):4219-4233.

Klein JD, Gorzkowski J, Resnick EA, Harris D, Kaseeska K, Pbert L, Prokorov A, Wang T, Davis J, Gotlieb E, Wasserman R. Delivery and Impact of a Motivational Intervention for Smoking Cessation: A PROS Study. Pediatrics. 2020;146(4).

Lasman L, Hanna JH, Novershtern N. Role of m6A in embryonic stem cell
differentiation and in gametogenesis. Epigenomes. 2020;4:5.

Lasman L, Krupalnik V, Viukov S, Mor N, Aguilera-Castrejon A, Schneir D, Bayerl J,
Mizrahi O, Peles S, Tawil S, Sathe S, Nachshon A, Shani T, Zerbib M, Kilimnik I, Aigner S, Shankar A, Mueller JR, Schwartz S, Stern-Ginossar N, Yeo GW, Geula S, Novershtern N, Hanna JH. Context-dependent functional compensation between Ythdf m(6)A reader proteins. Genes Dev. 2020;34(19-20):1373-1391.

Leni Z, Cassagnes LE, Daellenbach KR, El Haddad I, Vlachou A, Uzu G, Prevot ASH,
Jaffrezo JL, Baumlin N, Salathe M, Baltensperger U, Dommen J, Geiser M. Oxidative stress-induced inflammation in susceptible airways by anthropogenic aerosol. PLoS One. 2020;15(11):e0233425.

Lewis BW, Vo T, Choudhary I, Kidder A, Bathula C, Ehre C, Wakamatsu N, Patial S, Saini Y. Ablation of IL-33 Suppresses Th2 Responses but Is Accompanied by
Sustained Mucus Obstruction in the Scnn1b Transgenic Mouse Model. J Immunol. 2020;204(6):1650-1660.

Li Y, Pasunooti KK, Peng H, Li RJ, Shi WQ, Liu W, Cheng Z, Head SA, Liu JO. Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors. ACS Med Chem Lett. 2020;11(6):1111-1117.

Lin VY, Kaza N, Birket SE, Kim H, Edwards LJ, LaFontaine J, Liu L, Mazur M, Byzek SA, Hanes J, Tearney GJ, Raju SV, Rowe SM. Excess mucus viscosity and airway dehydration impact COPD airway clearance. Eur Respir J. 2020;55(1).

Liu D, Meister M, Zhang S, Vong CI, Wang S, Fang R, Li L, Wang PG, Massion P, Ji X. Identification of lipid biomarker from serum in patients with chronic obstructive pulmonary disease. Respir Res. 2020;21(1):242.

Margolies LR, Salvatore M, Tam K, Yip R, Bertolini A, Henschke CI, Yankelevitz DF.
Breast mass assessment on chest CT: Axial, sagittal, coronal or maximal intensity projection? Clin Imaging. 2020;63:60-64.

Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl
Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal
Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020;80(5):876-891 e876.

McGrath-Morrow SA, Gorzkowski J, Groner JA, Rule AM, Wilson K, Tanski SE, Collaco JM, Klein JD. The Effects of nicotine on development. Pediatrics. 2020;145(3).

Miller M, Ryan A, Reed RM, Goggins C, Sorkin J, Goldberg AP. Effect of Icosapent Ethyl on Gynoid Fat and Bone Mineral Health in the Metabolic Syndrome: A Preliminary Report. Clin Ther. 2020;42(11):2226-2230.

Myers V, Lev E, Guttman N, Tillinger E, Rosen L. “I can’t stand it…but I do it
sometimes” parental smoking around children: practices, beliefs, and conflicts – a qualitative study. BMC Public Health. 2020;20(1):693.

Myers V, Rosen LJ, Zucker DM, Shiloh S. Parental Perceptions of Children’s Exposure to Tobacco Smoke and Parental Smoking Behaviour. Int J Environ Res Public Health. 2020;17(10).

Myers V, Shiloh S, Zucker DM, Rosen LJ. Changing Exposure Perceptions: A
Randomized Controlled Trial of an Intervention with Smoking Parents. Int J Environ Res Public Health. 2020;17(10).

Navarro-Imaz H, Ochoa B, Garcia-Arcos I, Martinez MJ, Chico Y, Fresnedo O, Rueda Y. Molecular and cellular insights into the role of SND1 in lipid metabolism. Biochim Biophys Acta Mol Cell Biol Lipids. 2020;1865(5):158589.

Numata M, Mitchell JR, Tipper JL, Brand JD, Trombley JE, Nagashima Y, Kandasamy P, Chu HW, Harrod KS, Voelker DR. Pulmonary surfactant lipids inhibit infections with the pandemic H1N1 influenza virus in several animal models. J Biol Chem. 2020;295(6):1704-1715.

Oriano M, Gramegna A, Terranova L, Sotgiu G, Sulaiman I, Ruggiero L, Saderi L, Wu B, Chalmers JD, Segal LN, Marchisio P, Blasi F, Aliberti S. Sputum neutrophil elastase associates with microbiota and Pseudomonas aeruginosa in bronchiectasis. Eur Respir J. 2020;56(4).

Parks MJ, Kegler MC, Kingsbury JH, Borowsky IW. Reducing Socioeconomic
Disparities in Comprehensive Smoke-Free Rules among Households with Children: A Pilot Intervention Implemented through a National Cancer Program. Int J Environ Res Public Health. 2020;17(18).

Paz-Elizur T, Leitner-Dagan Y, Meyer KB, Markus B, Giorgi FM, O’Reilly M, Kim H, Evgy Y, Fluss R, Freedman LS, Rintoul RC, Ponder B, Livneh Z. DNA Repair Biomarker for Lung Cancer Risk and its Correlation With Airway Cells Gene Expression. JNCI Cancer Spectr. 2020;4(1):pkz067.

Peterson AL, Carr JF, Ji X, Dennery PA, Yao H. Hyperoxic Exposure Caused Lung Lipid Compositional Changes in Neonatal Mice. Metabolites. 2020;10(9).

Railwah C, Lora A, Zahid K, Goldenberg H, Campos M, Wyman A, Jundi B, Ploszaj M, Rivas M, Dabo A, Majka SM, Foronjy R, El Gazzar M, Geraghty P. Cigarette smoke induction of S100A9 contributes to chronic obstructive pulmonary disease. Am J Physiol Lung Cell Mol Physiol. 2020;319(6):L1021-L1035.

Rasmussen LW, Stanford D, Patel K, Raju SV. Evaluation of secondhand smoke
effects on CFTR function in vivo. Respir Res. 2020;21(1):70.

Rosen L, Kislev S, Bar-Zeev Y, Levine H. Historic tobacco legislation in Israel: a
moment to celebrate. Isr J Health Policy Res. 2020;9(1):22.

Salimi S, Yanosky JD, Huang D, Montressor-Lopez J, Vogel R, Reed RM, Mitchell BD, Puett RC. Long-term exposure to particulate air pollution and brachial artery flowmediated dilation in the Old Order Amish. Environ Health. 2020;19(1):50.

Sauler M. Form, Function, and Dysfunction: Airway Diseases Are Associated With Increased Risk for Rheumatoid Arthritis. Arthritis Rheumatol. 2020;72(5):699-701.

Steiger D, Han D, Yip R, Li K, Chen X, Liu L, Liu J, Ma T, Siddiqi F, Yankelevitz DF,
Henschke CI. Increased main pulmonary artery diameter and main pulmonary
artery to ascending aortic diameter ratio in smokers undergoing lung cancer
screening. Clin Imaging. 2020;63:16-23.

Stein Y, Aloni-Grinstein R, Rotter V. Mutant p53 oncogenicity: dominant-negative or gain-of-function? Carcinogenesis. 2020;41(12):1635-1647.

Sumsion JS, Pulsipher A, Alt JA. Differential expression and role of S100 proteins in chronic rhinosinusitis. Curr Opin Allergy Clin Immunol. 2020;20(1):14-22.

Sun F, Guo ZS, Gregory AD, Shapiro SD, Xiao G, Qu Z. Dual but not single PD-1 or TIM-3 blockade enhances oncolytic virotherapy in refractory lung cancer. J Immunother Cancer. 2020;8(1).

Timofte I, Wijesinha M, Vesselinov R, Kim J, Reed R, Sanchez PG, Ladikos N, Pham S, Kon Z, Rajagopal K, Scharf SM, Wise R, Sternberg AL, Kaczorowski D, Griffith B, Terrin M, Iacono A. Survival benefit of lung transplantation compared with medical management and pulmonary rehabilitation for patients with end-stage COPD. ERJ Open Res. 2020;6(2).

Tsai KYF, Hirschi Budge KM, Lepre AP, Rhees MS, Ajdaharian J, Geiler J, Epperson DG, Astle KJ, Winden DR, Arroyo JA, Reynolds PR. Cell invasion, RAGE expression, and inflammation in oral squamous cell carcinoma (OSCC) cells exposed to ecigarette flavoring. Clin Exp Dent Res. 2020;6(6):618-625.

Tsay JJ, Wu BG, Sulaiman I, Gershner K, Schluger R, Li Y, Yie TA, Meyn P, Olsen E, Perez L, Franca B, Carpenito J, Iizumi T, El-Ashmawy M, Badri M, Morton JT, Shen N, He L, Michaud G, Rafeq S, Bessich JL, Smith RL, Sauthoff H, Felner K, Pillai R, Zavitsanou AM, Koralov SB, Mezzano V, Loomis CA, Moreira AL, Moore W, Tsirigos A, Heguy A, Rom WN, Sterman DH, Pass HI, Clemente JC, Li H, Bonneau R, Wong KK, Papagiannakopoulos T, Segal LN. Lower airway dysbiosis affects lung cancer
progression. Cancer Discov. 2020.

Wakefield T, Glantz S. Blowing Smoke Out of the Bayou: The Battle for Tobacco
Control in Louisiana. UCSF: Center for Tobacco Control Research and Education
2020.

Wanders D, Hobson K, Ji X. Methionine Restriction and Cancer Biology. Nutrients. 2020;12(3).

Wang X, Rojas-Quintero J, Owen CA. “T”eeing Up A Novel Therapy for
Lymphangioleiomyomatosis. Am J Respir Cell Mol Biol. 2020;62(6):678-680.

Węziak-Białowolska D, Białowolski P, Mordukhovich I, McNeely ED. Work, Gender, and Sexual Harassment on the Frontlines of Commercial Travel: A Cross-Sectional Study of Flight Crew Well-Being,. The International Journal of Aerospace Psychology. 2020;30(3-4):171-189.

Wongtrakool C, Ko J, Jang AJ, Grooms K, Chang S, Sylber C, Kosmider B, Bahmed K, Blackburn MR, Sutliff RL, Hart CM, Park C, Nyunoya T, Passineau MJ, Lu Q, Kang BY. MicroRNA-98 reduces nerve growth factor expression in nicotine-induced airway remodeling. J Biol Chem. 2020;295(52):18051-18064.

Yofe I, Dahan R, Amit I. Single-cell genomic approaches for developing the next generation of immunotherapies. Nat Med. 2020;26(2):171-177.